Efficacy comparison of drug loaded microspheres in transcatheter arterial chemoembolization and laparoscopic precise hepatectomy for primary liver cancer
Objective:Compare the efficacy of drug-loaded microsphere transarterial catheter chemoembolization and laparoscopic precision liver resection for the treatment of primary liver cancer.Methods:A total of 105 primary liver cancer patients treated from March 2021 to November 2022 were selected as the study subjects,which were divided into 55 study groups and 50 control groups according to the random number table method.The control group used laparoscopic precision hepatectomy,and the study group used drug-loaded microsphere transarterial catheter chemoembolization.The liver function,T lymphocyte subsets,quality of survival,stress indicators,and occurrence of complications within six months were surgery.Results:On the third day after surgery,the AST,ALT,TBiL,E,NE,and IL-6 increased in both groups,but the study group was lower than that in the control group(P<0.05).On the third day after surgery,CD3+and CD4+decreased in both groups,but the study group was higher than the control group,and CD8+increased,but the study group was lower than the control group(P<0.05).On the third day after surgery,the scores of social function,role function,physical function,cognitive function,and emotional function were increased in the two groups,and the study group was higher than the control group(P<0.05).Compared with the control group,the overall incidence of abdominal effusion,hemorrhage,pulmonary infection,and biliary fistula was lower in the study group(P<0.05).Conclusion:Drug-loaded microsphere transarterial catheter chemoembolization and laparoscopic precision hepatocatectomy achieved good results,but drug-loaded microsphere transarterial catheter chemoembolization had a more obvious effect on liver function regulation,with low complication rate,relatively high safety degree,and good clinical effect.
primary liver cancertranscatheter arterial chemoembolization with drug loaded microsphereslaparoscopic precise hepatectomyefficacy comparison