The study based on the knowledge coding of traditional Chinese patent medicines in Chinese Pharmacopoeia and medication rules of liver system syndrome
According to the planning and requirements of the clinical big data knowledge project of traditional Chinese medicine,a clinical database of traditional Chinese patent medicines based on the Chinese pharmacopoeia was constructed,and data of traditional Chinese patent medicines for the treatment of liver diseases were extracted from the database.According to the standards of the classification and code of diseases and syndromes in traditional Chinese medicine(GB/T 15657-2021)and the classification and codes of Chinese medicinals in clinical practice(T/CIATCM 024-2019),along with the clinical knowledge coding model of traditional Chinese patent medicines.We have coded the data of traditional Chinese patent medicines for the treatment of liver diseases,including prescription compatibility,monarch and functional indications,which has led to the construction of a clinical knowledge base for traditional Chinese patent medicines for the treatment of liver diseases.In total,there are 214 pieces of clinical medication knowledge for traditional Chinese patent medicines and simple preparations,comprising 77 pieces of medication knowledge for single syndrome of the liver system and 137 pieces for combined viscera and syndrome of the liver system.Conducting distribution pattern analysis and visualization research on the clinical knowledge of Chinese patent medicines in this database using classical statistical methods.And use GraphDB tool to draw the knowledge map of traditional Chinese patent medicines for clinical use of liver diseases and syndromes,and build the knowledge map database of traditional Chinese patent medicines for clinical use of liver diseases and syndromes in the Chinese Pharmacopoeia.In this work,taking Chinese patent medicines for treating liver excess syndromes as an example,we have illustrated their knowledge graph,showcasing the interrelationships within the clinical knowledge of Chinese patent medicines.This study provides clinical knowledge resources of traditional Chinese patent medicines in the Chinese pharmacopoeia for in-depth clinical prescription decision-making of liver diseases and syndromes.
traditional Chinese patent medicineclinical knowledgeliver diseasesknowledge codingknowledge graph