Relationship between Traditional Chinese Medicine Syndrome Pattern and Risk Factors of Acute Myocardial Infarction
Objective:To explore the relationship between traditional Chinese medicine(TCM)syndrome types and cardiovascular risk factors of acute myocardial infarction(AMI).Methods:A total of 1 204 cases of AMI were analyzed retrospectively,SPSS software was used to describe the frequency distribution of each syndrome type,chi square test was used to test whether there were the distribution of mde and femde among each syndrome type,one-way ANOVA and nonparametric test were used to compare the differences of each syndrome type in gender,age,body mass index(BMI),days of hospital stay and biochemical indexes,and binary Logistic regression was used to explore the relationship between main TCM syndrome types and various indexes.Results:The distribution of TCM syndromes in 1 204 cases of AMI was as follows:heart and lung Qi deficiency syndrome(3.3%)<Qi deficiency and blood stasis syndrome(3.4%)<Qi stagnation and blood stasis syndrome(4.5%)<heart yang deficiency and failure syndrome(7.3%)<phlegm turbidity and blood stasis syndrome(7.8%)<heart pulse obstruction syndrome(18.6%)<Qi and Yin deficiency syndrome(24.1%)<phlegm turbidity congestion syndrome(31.0%).There were differences in gender distribution of TCM syndrome types of AMI.Age of onset:phlegm turbidity congestion syndrome was significantly lower than that of Qi and Yin deficiency syndrome,Qi Deficiency and Blood stasis syndrome,Qi stagnation and blood stasis syndrome,and heart yang deficiency and decline syndrome(P<0.05).Body weight:Qi and Yin deficiency syndrome was significantly lower than that of phlegm congestion syndrome,heart blood stasis syndrome,and phlegm turbidity and blood stasis syndrome(P<0.05).Days of hospital stay:phlegm turbidity and blood stasis syndrome and phlegm turbidity congestion syndrome were significantly less than that of Qi and Yin deficiency syndrome(P<0.05).Red blood cell count(RBC)and hemoglobin concentration(Hb):phlegm congestion syndrome and heart blood stasis syndrome were significantly higher than Qi and Yin deficiency syndrome(P<0.05),but there was no significant difference between phlegm congestion syndrome and heart blood stasis syndrome.Diastolic blood pressure(DBP)and triglyceride(TG):phlegm congestion was significantly higher than Qi and Yin deficiency syndrome(P<0.05).High density lipoprotein(HDL-C):the syndrome of phlegm turbidity obstruction was significantly lower than that of Qi and Yin deficiency(P<0.05).Binary Logistic regression showed that TG was an independent risk factor of phlegm congestion syndrome,and age,days of hospital stay,and HDL-C were protective factors of phlegm congestion syndrome of AMI.Body weight was an independent risk factor of phlegm turbidity and blood stasis syndrome of AMI,while body weight and Hb were protective factors of Qi and Yin deficiency syndrome in AMI(P<0.05).Conclusion:Gender,age,between of hospital stay,RBC,body weight,Hb,DBP,TG,HDL-C,and other indicators show certain differences between TCM syndrome types of AMI,and there are some relationship the main TCM syndrome types and AMI,which can be used as some clinical reference for TCM syndrome differentiation and early identification of AMI.
acute myocardial infarctiontraditional Chinese medicine syndrome typerisk factorscorrelation