Literature Analysis on the Evolution of TCM Syndromes and Syndrome Element in Heart Failure Patients with Different NYHA Grades
Objective:To summarize the traditional Chinese medicine(TCM)syndrome types and syndrome elements of heart failure with different NYHA grades.Methods:Using China National Knowledge Infrastructure(CNKI)database,Wanfang database,VIP Chinese Journal Database,PubMed,and Web of Science(WOS)as data sources,literature related to TCM syndromes and syndrome elements of heart failure was retrieved from self-established database to September 1,2022.SPSS 27.0 was used to count the number of syndrome cases and frequency of syndrome elements in patients of each grade under NYHA classification,and the distribution of syndrome types was analyzed according to the frequency/component ratio.Results:A total of 48 articles were included in this study,with 10 058 cases.The syndrome with frequency≥3.00%was considered as the common syndrome,including Qi deficiency and blood stasis syndrome,Qi deficiency and Yin deficiency syndrome,phlegm turbidity and lung obstruction syndrome,Yang deficiency and water deficiency syndrome,heart-kidney Yang deficiency syndrome,cardiopulmonary Qi deficiency,heart Qi deficiency and Yin deficiency and blood stasis,Qi deficiency and blood stasis phlegm retention,and blood stasis syndrome.The syndrome elements with frequency≥3.00%were considered as the common elements,including Qi deficiency,blood stasis,Yang deficiency,Yin deficiency,water retention,and phlegm turbidity.The common disease syndrome elements included heart,lung,kidney,and spleen.Conclusion:Heart failure is mainly located in the heart,which is closely related to lung,kidney and spleen.Among the patients with different NYHA grades,the main syndrome of gradeⅠ was Qi deficiency,blood stasis and phlegm retention,followed by cardiopulmonary Qi deficiency and heart Qi deficiency.The main syndrome elements were Qi deficiency and blood stasis.The main syndroms of grade Ⅱ were Qi deficiency and blood stasis syndrome,heart Qi deficiency and Yin deficiency syndrome,cardiopulmonary Qi deficiency syndrome and Qi Yin deficiency and blood stasis syndrome.The most prominent syndromes were Qi retention,followed by blood stasis and Yin deficiency.The main syndrome of grade Ⅲ was Qi deficiency and blood stasis syndrome,Qi and Yin deficiency syndrome,Yang deficiency and water deficiency syndrome,cardiopulmonary Qi deficiency syndrome,and the pathogenic syndrome elements were Qi deficiency,blood stasis and Yang deficiency.The main symptoms of grade Ⅳ were Yang deficiency and water flooding syndrome,Qi deficiency and blood stasis syndrome,phlegm turbidity and lung obstruction syndrome,and the pathogenic syndrome elements were Qi deficiency,Yang deficiency,blood stasis,and water drinking in order.
heart failuresyndromeelementcardiac function gradeliterature analysis
万方数据
维普
