Medication Rule of the Chinese Medical Master Lei Zhongyi for the Treatment of Coronary Heart Disease after PCI Based on Data Mining
Objective:To analyze and summarize the medication rules of Chinese medical master Lei Zhongyi for the treatment of coronary heart disease after percutaneous coronary intervention(PCI)based on data mining.Methods:The prescription medications of Chinese Medical Master Lei Zhongyi for treatment of coronary artery disease after PCI from January 2014 to June 2022 were collected and organized.Excel 2019,IBM SPSS Statistics 25.0,SPSS Modeler 18.0,Cytoscape3.9.1 and other software were used to perform frequency statistics,drug flavor classification analysis,association rule analysis,cluster analysis,and complex network analysis for included prescription drugs.Results:After screening,there were 61 prescriptions included,36 involved Chinese patent medicines,and a total of 128 flavors were included.The top 10 high-frequency drugs were salvia miltiorrhiza,schisandra,Notoginseng,ophiopogon,Tangerine peel,Astragalus,Gualou,Allium Macrostemon,Coptis,ginseng.The four qi of medicine were mainly warm,cold and flat,the five flavors were mainly bitter,sweet and xin,and the channel entry were mainly lung,liver,heart and spleen.The association rules showed that the commonly drug combinations were Schisandra chinensis-maitake,danshen-panax ginseng,and the commonly used angiosperms were schisandra chinensis-chenpi-maitake,danshen-chenpi-maitake.The cluster analysis showed there were 4 cluster combinations,and the complex network found that the core formula was Yangxin Huoxue Decoction by Lei Zhongyi.Conclusion:Chinese Medical Master Lei Zhongyi treated coronary heart disease after PCI from the"phlegm stasis",focusing on the elimination of evil and support both positive,with self-formulated prescription Yangxin Huoxue Decoction,dynamic identification,add and subtract according to the evidence.
NETL
NSTL
万方数据
维普
