Influence of Yiqi Huoxue Decoction on Convalescent Patients with Myocardial Infarction
Objective:To observe the effect of Yiqi Huoxue decoction on convalescent patients with myocardial infarction.Methods:A total of 144 patients with myocardial infarction in recovery period were selected as the study objects,and the patients were divided into Buyang Huanwu Granule group(31 cases),Naoxintong Capsule group(49 cases),Yangyin Tongnao Granule group(31 cases)and control group(33 cases)by random number method.Buyang Huanwu Granules group was given standardized treatment+Buyang Huanwu Granules+capsule simulation agent,Naoxintong Capsules group was given standardized treatment+Naoxintong Capsules+ granule simulation agent,Yangyin Tongnao Granules group was given standardized treatment+Yangyin Tongnao Granules+capsule simulation agent,and control group was given standardized treatment + granule simulation agent + capsule simulation agent.Continuous treatment for 3 months.Left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),the level of N-terminal B-type natriuretic peptide(NT-proBNP),the change rate of NT-proBNP,traditional Chinese medicine(TCM)syndrome score,and the curative effect of TCM syndrome were observed in each group before and after treatment.Results:After treatment,the level of LVEF in Buyang Huanwu Granule group,Naoxintong Capsule group and Yangyin Tongnao Granule group were higher than that before treatment,and better than that in control group(P<0.05).There were no significant differences in LVEDD and LVESD levels among Buyang Huanwu Granule group,Naoxintong Capsule group and Yangyin Tongnao Granule group compared with that before treatment(P>0.05).After treatment,the levels of NT-proBNP in Buyang Huanwu Granule group and Naoxintong Capsule group were lower than that before treatment(P<0.05).Taking NT-proBNP decreased by 30%as the standard,patients with NT-proBNP decreased by≥30%in Buyang Huanwu Granule group were more than that in other 3 groups(P<0.05).After treatment,the scores of chest pain in Naoxintong Capsule group and Yangyin Tongnao Granule group were better than those in control group(P<0.05).The sweating score of Naoxintong Capsule group decreased compared with that before treatment(P<0.05).After treatment,the purple and dark complexion score and total score of Naoxintong Capsule group were better than those of control group(P<0.05).Buyang Huanwu Granules could relieve the symptoms of fatigue,Naoxintong Capsules could relieve the symptoms of chest tightness and shortness of breath,and could more comprehensively reduce the clinical symptoms of patients.Conclusion:Buyang Huanwu Granules,Naoxintong Capsules and Yangyin Tongnao Granules can improve the cardiac function and clinical symptoms in patients with myocardial infarction during recovery.
万方数据
维普
