Clinical Study of PCI Combined with Intra-aortic Balloon Counterpulsation for the Treatment of Elderly Patients with Acute Myocardial Infarction Complicated with Heart Failure
Objective:To explore the clinical effect of percutaneous coronary intervention(PCI)combined with intra-aortic balloon counterpulsation(IABP)for elderly patients with acute myocardial infarction(AMI)complicated with heart failure.Methods:A total of 103 elderly patients with AMI complicated with heart failure were retrospectively selected,including 52 patients treated with IABP combined with PCI as the combination group,and 51 patients treated with PCI only during the same period as the control group.The TIMI blood flow grade,myocardial enzymologic index,cardiac function index,and incidence of adverse cardiovascular events(MACE)were compared between the two groups after treatment.Results:After treatment,the TIMI blood flow grading of target vessel in combination group was better than that in the control group(P＜0.05).After treatment,serum levels of creatine kinase isoenzyme(CK-MB),troponin l(cTnl),lactate dehydrogenase(LDH),and troponin T(cTnT)in two groups decreased compared with those before treatment(P＜0.05),but there were no statistical significance between the two groups after treatment(P＞0.05).After treatment,the left ventricular ejection fraction(LVEF)of combination group was higher than that of the control group,but the left ventricular end-systolic diameter(LVESD)and the N-terminal pro-B-type natriuretic peptide(NT-proBNP)of combination group were lower than that of the control group,with statistical significance(P＜0.05).After 24 months of follow-up,the incidence of MACE in combination group was 5.77％,lower than that 21.57％in the control group,and the difference was statistically significant(P＜0.05).Conclusion:IABP combined with PCI for the treatment of elderly patients with AMI complicated with heart failure can promote the recovery of cardiac function and target blood flow,and reduce the incidence of MACE.
万方数据
维普
