Relationship between Nutritional Status and Adverse Cardiac Events in Elderly Patients with Chronic Heart Failure
Objective:To explore the relationship between nutritional status and adverse cardiac events in elderly patients with chronic heart failure(CHF).Methods:A total of 102 elderly CHF patients were selected and divided into malnutrition group(41 cases),malnutrition risk group(33 cases),and better nutrition group(28 cases)according to Mini Nutrition Assessment(MNA)score.Thyroid hormone(TH)indexes and cardiac function indexes were compared among the three groups.The incidence of adverse cardiac events in 3 groups were recorded,and the correlation between the incidence of adverse cardiac events and nutritional indexes was analyzed.Results:The levels of triiodothyronine(T3)and free triiodothyronine(FT3)in malnutrition group were significantly lower than those in malnutrition risk group and good nutrition group(P＜0.05).The levels of T3 and FT3 in malnutrition risk group were significantly lower than those in good nutrition group(P＜0.05).There were no significant difference in thyroid hormone(T4),free thyroid hormone(FT4)and thyroid stimulating hormone(TSH)among the three groups(P＞0.05).Left ventricular ejection fraction(LVEF)in malnutrition group was significantly lower than that in malnutrition risk group and better nutrition group,while left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD)and N-terminal pro brain natriuretic peptide(NT-proBNP)were significantly higher than those in malnutrition risk group and good nutrition group(P＜0.05).LVEF in malnutrition risk group was significantly lower than that in good nutrition group,while LVEDD,LVESD and NT-proBNP were higher than those in better nutrition group(P＜0.05).The incidence of adverse cardiac events in malnutrition group was significantly higher than that in malnutrition risk group and better nutrition group(P＜0.05).The incidence of adverse cardiac events in malnutrition risk group was slightly higher than that in better nutrition group,but there was no significant difference between the two groups(P＞0.05).Hemoglobin(Hb),prealbumin(PAB)and albumin(ALB)in patients with cardiac adverse events were significantly lower than those without cardiac adverse events(P＜0.05).Correlation analysis showed that adverse cardiac events were negatively correlated with nutritional indexes(P＜0.05).Conclusion:The worse the nutritional status of elderly CHF patients,the higher the risk of adverse cardiac events,which may be related to the influence of malnutrition on T3,FT3 and cardiac function indexes.
chronic heart failureelderly patientsnutritional statusadverse cardiac eventcardiac function
万方数据
维普
