Effects of Guanxin Danshen Dropping Pills on Quality of Life and Blood Stasis Syndrome Score in Patients with Acute Coronary Syndrome Complicated with Type 2 Diabetes Mellitus after PCI
Effects of Guanxin Danshen Dropping Pills on Quality of Life and Blood Stasis Syndrome Score in Patients with Acute Coronary Syndrome Complicated with Type 2 Diabetes Mellitus after PCI
Objective:To observe the effects of Guanxin Danshen Dropping Pills on quality of life and blood stasis syndrome score in patients with acute coronary syndrome(ACS)complicated with type 2 diabetes mellitus(T2DM)after percutaneous coronary intervention(PCI).Methods:The patients with ACS combined with T2DM who underwent PCI from February 2012 to December 2015 were enrolled in 40 medical centers in China,and they were divided into Guanxin Danshen dropping pill group and conventional treatment group according to whether Guanxin Danshen dropping pill was used as exposure factor.The patients of conventional treatment group were treated with conventional western medicine as recommended by the guidelines,and the patients of the Guanxin Danshen dropping pill group were also treated with Guanxin Danshen dropping pill 0.4 g each time,3 times a day,for 12 months.Seattle Angina Pectoris Scale(SAQ)and blood stasis syndrome score were used as evaluation indexes,and generalized estimation equation(GEE)was used for statistical analysis.Results:Six hundred and fifty patients completed follow-up,including 340 patients in the Guanxin Danshen dropping pill group and 310 patients in the conventional treatment group.Compared with the conventional treatment group,the total score of SAQ in the Guanxin Danshen dropping pill group increased at the 12th month of treatment(P＜0.05),and the score of blood stasis syndrome decreased significantly at the 6th and 12th months of treatment(P＜0.05 or P＜0.01).Conclusion:Guanxin Danshen dropping pills could improve the SAQ score,reduce the score of blood stasis syndrome,and improve the quality of life in ACS patients with T2DM after PCI.
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