Analysis of Clinical Features and Risk Factors of Cardiogenic Ischemic Stroke
Objective:To analyze the clinical features and risk factors of cardiogenic ischemic stroke.Methods:Two hundred and ten ischemic stroke patients admitted to Guang'an People's Hospital from November 2019 to November 2022 were selected.According to TOAST classification,there were 42 cases diagnosed as cardiogenic stroke,73 cases as large atherosclerotic stroke,66 cases as lacunar stroke and 29 cases as unknown cause stroke.Echocardiographic parameters of stroke patients with different TOAST classification were compared to analyze the influencing factors of cardiogenic ischemic stroke.The diagnostic value of echocardiographic parameters combined with D-dimer in cardiogenic ischemic stroke was evaluated.Results:The left atrial diameter(LAD)of cardiogenic ischemic stroke patients was larger than that of other TOAST stroke patients,the left ventricular ejection fraction(LVEF)and stroke volume(SV)were smaller than those of other TOAST stroke patients,and the levels of D-dimer and N-terminal B-type natriuretic peptide precursors were higher than those of other TOAST stroke patients,the differences were statistically significant(P<0.05).Multiple Logistic regression analysis showed that D-dimer,LAD were the risk factors of cardiogenic ischemic stroke(P<0.05).Receiver operating characteristics(ROC)curves showed that the area under the curve(AUC)of D-dimer,LAD and SV in the diagnosis of cardiogenic ischemic stroke were 0.737,0.751,and 0.711 respectively,and the cutoff values were 291.32 ng/mL,37.57 mm,and 70.16 mL,respectively.The AUC of the combined diagnosis was 0.853,and the sensitivity and specificity were 73.81%and 91.07%respectively.Conclusion:The patients with cardiogenic ischemic stroke showed more LAD and less LVEF and SV.D-dimer,LAD,and SV were the risk factors for cardiogenic ischemic stroke.LAD and SV combined with D-dimer had certain diagnostic value for cardiogenic ischemic stroke,and could assist for the rapid screening of patients with cardiogenic ischemic stroke.