Medication Rules for Traditional Chinese Medicine for the Treatment of Chronic Heart Failure with Depression Based on Data Mining
Objective:To explore the medication rules of traditional Chinese medicine for the treatment of chronic heart failure with depression based on data mining.Methods:The literatures for chronic heart failure with depression using traditional Chinese medicine published in China National Knowledge Infrastructure(CNKI),Wipro Chinese Full-text Database of Scientific and Technological Journals(VIP),Wanfang Data and Chinese Biomedical Literature databases were collected and sorted out.The search period was from the establishment of the database to May 2023.The prescriptions were entered into Excel tables,and then imported into the traditional Chinese medicine(TCM)Inheritance Assistance Platform(V2.5)software.Data mining technologies such as basic information statistics,frequency analysis,association rule analysis and hierarchical clustering were used to analyze the medical records to explore the medication rules and new prescriptions.Results:A total of 42 prescriptions were included,involving 88 single herbs.Frequency analysis results showed that poria,atractylodes,bupleurum,radix paeoniae alba,aconite,radi glycyrrhizae preparatae,salvia,ginseng,radix astragali,and ligustici ranked top ten popular drug.The medicinal natures were mainly warm,cold and plain.The main medicinal flavour was sweet,followed by bitter and pungent,and the channel tropism were heart,liver and spleen channels.A total of 50 popular drugs combinations,31 drugs association rules,and 5 potential new prescriptions were obtained.Conclusion:The basic treatment of chronic heart failure with depression with traditional Chinese medicine are to supplement Qi and warm yang,soothe liver-Qi stagnation,and to promote blood circulation for removing blood stasis,clear damp and promote diuresis.
chronic heart failuredepressiontraditional Chinese medicinedata miningmedication rules
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万方数据
