Meta-analysis of Boost Qi,Dissolve Phlegm and Invigorate Blood for the Treatment of Cardiovascular Metabolic Diseases
Objective:To systematically evaluate the effect and safety of boost Qi,dissolve phlegm and invigorate blood for the treatment of cardiovascular metabolic diseases.Methods:Randomized controlled trials(RCTs)for the treatment of cardiovascular metabolic diseases by boost Qi,dissolve phlegm and invigorate blood were searched from Chinese and English databases.Data extraction and quality evaluation were conducted by RevMan 5.4 software,and Meta-analysis was performed.Results:A total of 24 literatures were included,including 1 951 patients,with 980 patients in the observation group and 971 patients in the control group.The results of Meta-analysis showed that compared with the control group,the clinical efficacy in the observation group was better(OR=5.09,95％CI 3.67-7.07,P＜0.000 01);fasting blood glucose(MD=-0.68,95％CI-1.06--0.30,P=0.000 4),2 h postprandial blood glucose(MD=-1.37,95％CI-1.62--1.12,P＜0.000 01),glycosylated hemoglobin(MD=-0.56,95％CI-0.72--0.41,P＜0.000 01),total cholesterol(MD=-0.69,95％CI-1.29--0.08,P=0.03),triacylglycerol(MD=-0.47,95％CI-0.58--0.36,P＜0.000 01),low density lipoprotein cholesterol(MD=-0.61,95％CI-0.72--0.51,P＜0.000 01),interleukin-6(SMD=-0.36,95％CI-0.59--0.13,P=0.002),tumor necrosis factor-α(SMD=-1.16,95％CI-2.13--0.19,P=0.02),C-reactive protein(SMD=-0.83,95％CI-1.63--0.04,P=0.04),body mass index(MD=-0.92,95％CI-1.33--0.52,P＜0.000 01),traditional chinese medicine syndrome score(MD=-2.79,95％CI-3.96--1.62,P＜0.000 01)in the observation group was less than that of control group,and the differences were statistically significant.Left ventricular ejection fraction in the observation group was more than that in the control group,and the difference was statistically significant(SMD=1.15,95％CI 0.62-1.69,P＜0.000 1).Conclusion:The current evidence showed that boost Qi,dissolve phlegm and invigorate blood for the treatment of cardiovascular metabolic diseases was effective,with fewer adverse reactions.
cardiovascular metabolic diseasesboost Qi,dissolve phlegm and invigorate bloodcurative effectsafetyMeta-analysis
万方数据
维普
