Prognostic Value of NLR,Cystatin C and Hypersensitivity Troponin Ⅰ on Complications of Acute Myocardial Infarction in Different Age Groups
Objective:To investigate the clinical value of laboratory indicators for predicting complications of acute myocardial infarction(AMI)in different age groups.Methods:One hundred and sixty-two patients were divided into the young and middle-aged group(18-74 years old,86 cases),elderly group(75-99 years old,76 cases),clinical data and laboratory indicators were collected.According to the complication of heart failure,cardiogenic shock,arrhythmia and other complications,the young and middle-aged group and the old group were divided into complication group and non-complication group,there were 53 cases in the young and middle-aged complications group and 33 cases in the young and middle-aged non-complications group,there were 46 cases in the elderly complication group and 30 cases in the elderly non-complication group.Receiver operating characteristic(ROC)curve was used to evaluate the predictive value of complications of AMI patients.Results:The male proportion,smoking history proportion,high total cholesterol(TC)and triacylglycerol(TG)in the young and middle-aged group were more than those in the elderly group,and the glycosylated hemoglobin(HbA1c)was less than that in the elderly group,with statistical significance(P＜0.05).Cystatin C(CysC),hypersensitive troponin Ⅰ(hs-TnⅠ),neutrophil/lymphocyte ratio(NLR),neutrophil(Neu)and white blood cell count(WBC)in the young and middle-aged complications group were more than those in the young and middle-aged non-complications group,and lymphocyte(Lym)was less than that in the young and middle-aged non-complications group,with statistical significance(P＜0.001).The levels of CysC,hs-TnⅠ,NLR,Neu,WBC and TG in the elderly complication group wre more than those in the elderly non-complications group,and the Lym was less than that in the elderly non-complications group,with statistical significance(P＜0.05).The area under ROC curve(AUC)of CysC,hs-TnⅠ,NLR and Neu were 0.74,0.85,0.83 and 0.82,respectively.The AUC of CysC,hs-TnⅠ,NLR in the elderly group were 0.75,0.77 and 0.79,respectively.Conclusion:There were differences in lifestyle and laboratory indicators in AMI patients of different ages.Age and physiological characteristics should be considered in the diagnosis and treatment of AMI patients.Laboratory indicators such as CysC,hs-TnⅠ,NLR and Neu could predict the complications of AMI patients.
万方数据
维普
