首页|基于中医传承辅助平台探讨中药治疗高血压的用药规律

基于中医传承辅助平台探讨中药治疗高血压的用药规律

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目的:基于中医传承辅助系统软件探讨中药治疗高血压的用药规律。方法:收集2020年1月 2023年1月就诊于河南中医药大学第一附属医院心血管内科且第一诊断为高血压病人的病案,建立数据库,利用中医传承辅助系统的频次统计、关联规则及复杂系统熵聚类等统计方法对数据进行分析。结果:筛选出治疗原发性高血压的医案374例,涉及中药225味;发现最为常见的4个证型分别是肝阳上亢证、痰湿中阻证、痰瘀互结证、气血亏虚证;药性以寒、温、平为主,药味以甘、苦为主,归经以肝、脾、胃为多;使用频次较高的中药依次为茯苓、白术、甘草、天麻、丹参、黄芩、柴胡、葛根、清半夏、白芍。获得核心药物组合10个、新方5首。结论:中药治疗原发性高血压以平肝潜阳为主,以益气活血、清热利湿、健脾为辅。
Exploration of the Medication Patterns of Traditional Chinese Medicine for the Treatment of Primary Hypertension Based on the Auxiliary Platform for Traditional Chinese Medicine Inheritance
Objective:To explore the medication regulations of traditional Chinese medicine for treating essential hypertension using the Traditional Chinese Medicine Inheritance Assistant System software.Methods:The medical records of patients who were admitted to the Cardiovascular Department of the First Affiliated Hospital of Henan University of Chinese Medicine between January 2020 to January 2023 and who were initially diagnosed with hypertension were collected,and the database was established.The data were analyzed using the statistical methods of frequency statistics,association rules,and complex system entropy clustering of the Traditional Chinese Medicine Inheritance Auxiliary System.Results:A total of 374 medical records were screened for the treatment of primary hypertension,involving 225 traditional Chinese medicines.The four most common types of syndromes were hyperactivity of liver yang,obstruction of phlegm dampness of phlegm and blood stasis,and deficiency of qi and blood.The medicinal properties were mainly cold,warm,and flat,and the medicinal taste was mainly sweet and bitter.The meridians mainly focused on the liver,spleen,and stomach.The popular traditional Chinese medicine were Poria cocos,Atractylodes macrocephala,Glycyrrhiza uralensis,Gastrodia elata,Salvia miltiorrhiza,Scutellaria baicalensis,Bupleurum chinense,Pueraria lobata,Pineilia ternata,and Paeonia lactiflora.A total of 10 core drug combinations and 5 new prescriptions were obtained.Conclusion:Traditional Chinese medicine is mainly used to treat primary hypertension by calming the liver and suppressing yang,with supplementing qi and promoting blood circulation,clearing heat and dampness,and strengthening the spleen.

hypertensionTraditional Chinese Medicine Inheritance Assistance Platformmedication patternsdata mining

刘晓萌、刘高卿、曹园圆、谢梦欣、闫奎坡

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河南中医药大学第一附属医院心脏中心/国家区域(中医)心血管诊疗中心(郑州 450000)

河南中医药大学第一临床医学院(郑州 450000)

河南中医药大学骨伤学院

高血压 中医传承辅助平台 用药规律 数据挖掘

2024

中西医结合心脑血管病杂志
中国中西医结合学会 山西医科大学第一医院

中西医结合心脑血管病杂志

CSTPCD
影响因子:1.463
ISSN:1672-1349
年,卷(期):2024.22(19)