首页|基于古今医案云平台探索国医大师治疗心力衰竭的组方用药规律

基于古今医案云平台探索国医大师治疗心力衰竭的组方用药规律

扫码查看
目的:探讨国医大师治疗心力衰竭的组方用药规律。方法:搜集中国知网、万方、维普、中国生物医学文献数据库及古今医案云平台中所有国医大师治疗心力衰竭的临床经验医案,建立方药数据库并应用"古今医案云平台V2。3。6"的频数统计、关联分析、复杂网络分析、聚类分析等方法进行数据挖掘。结果:检索到37位国医大师的完整处方,纳入方剂195首,包括经典方剂和自拟方剂,涉及中药312味,频次≥40次的药物21味,前5位分别是黄芪、茯苓、丹参、麦冬、白术,四气以温、平为主,五味以甘、辛、苦为主,归经主要以肺、脾、心、肝为主,以活血化瘀、健脾益气、利水、滋阴养血、温阳化气类药物出现频数最高,挖掘出26组常用药对,聚类分析得到4个中药组合。结论:心力衰竭以本虚标实、虚实夹杂为基本病机,临床多以益气温阳、滋阴养血的药物治疗本虚,以活血化瘀、利水之品治疗标实。不同国医大师临证时亦有独特的辨治经验,如五脏相关,整体辨治;重视原发,分期诊治;虚瘀水停,扶正祛邪;理论创新,灵活辨治。
Medication Regularity of Traditional Chinese Medicine Masters for Treating Heart Failure Based on Ancient and Modern Medical Record Cloud Platform
Objective:To explore the rules of prescription medication for treating heart failure by traditional Chinese medicine(TCM) masters.Methods:The clinical experience of all TCM masters for the treatment of heart failure was collected from China National Knowledge Infrastructure(CNKI),Wanfang,VIP,China Biomedical Database and Ancient and Modern Medical Cloud Platform.The prescription database was established. The frequency statistics,association analysis,complex network analysis,cluster analysis and other methods of "Ancient and Modern Medical Records Cloud Platform V2.3.6" were used for data mining. Results:The complete medical cases of 37 TCM masters were retrieved,and 195 prescriptions were included,including classic prescriptions and self-prepared prescriptions.There were 312 TCM medicines and 21 TCM drugs with frequency ≥40 times,the top 5 were Astragali Radix,Poria,Salvia Miltiorrhiza,Ophiopogon Japonicus,and Atractylodis Macrocephalae Rhizoma.The four properties were mainly warm and flat,the five tastes were mainly sweet,pungent and bitter,and the attributive channel were lung,spleen,heart,and liver.Promoting blood circulation and removing blood stasis,strengthening spleen and replenishing Qi,disinhibiting water,nourishing Yin and supplementing blood,warming Yang and promoting Qi were the most frequent drugs.Twenty-six groups of common drug pairs were excavated,and 4 combinations of drug were obtained by cluster analysis. Conclusion:The basic pathogenesis of heart failure are deficiency and superficiality.The clinical treatment of benefiting Qi and warming Yang,nourishing Yin and supplementing blood are applied clinically to treat deficiency with the highest frequency,while drugs of activating blood and removing blood stasis,inhibiting water were applied to treat excess in superficiality.Different TCM masters have unique clinical experience for treating heart failure,some masters focus on correlation of five vicera,holistic treatment based on syndrome differentiation;some masters focus on the primary disease and staging diagnosis and treatment;some masters focus on deficiency,stasis and water retention,strengthening healthy Qi to eliminate pathogens;some masters focus on innovation in theories,flexible differentiation treatment.

heart failuretraditional Chinese medicine mastermedicine rulesdiagnosis and treatment characteristicsAncient and Modern Medical Record Cloud Platform

丁姝辰、张贺、陈宣晔、徐浩

展开 >

北京中医药大学 北京 100029

中国中医科学院西苑医院 北京 100091

国家中医心血管病临床医学研究中心 北京 100101

心力衰竭 国医大师 用药规律 诊疗特点 古今医案云平台

2024

中西医结合心脑血管病杂志
中国中西医结合学会 山西医科大学第一医院

中西医结合心脑血管病杂志

CSTPCD
影响因子:1.463
ISSN:1672-1349
年,卷(期):2024.22(23)