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木芙蓉花的化学成分研究(Ⅱ)

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目的:对锦葵科木槿属植物木芙蓉Hibiscus mutabilis L.的花进行化学成分研究.方法:采用硅胶柱色谱、ODS柱色谱、制备型高效液相色谱等多种分离纯化技术对木芙蓉花的90%乙醇提取物进行分离纯化,并根据核磁数据进行结构鉴定.结果:从木芙蓉花中分离纯化得到17个化合物,分别鉴定为:和厚朴酚(1)、厚朴酚(2)、iso-hemigossylic acid lactone-2-methyl ether(3)、阿魏酸(4)、3-吲哚甲醛(5)、脱落酸(6)、槲皮素(7)、山柰酚(8)、8-(1-(3,4-dihydroxyphenyl)ethyl-3,3',4',5,7-pentahydroxyflavone)(9)、环(脯-缬)二肽(10)、benzyl-β-D-glucopyranoside(11)、山柰酚-3-O-β-D-葡萄糖苷(12)、rhodionin(13)、槲皮素-3-O-(6"-O-反式-对香豆酰基)-β-D-吡喃葡萄糖苷(14)、tiliroside(15)、山柰酚-3-O-(6"-O-顺式-对香豆酰基)-β-D-吡喃葡萄糖苷(16)、山柰酚-7-O-α-L-吡喃鼠李糖苷(17).结论:其中,化合物1~3、5、6、9~11、14为首次从木槿属植物中分离得到.
Chemical Constituents from the Flowers of Hibiscus mutabilis(Ⅱ)
Objective:To study the chemical constituents from the flowers of Hibiscus mutabilis.Methods:The 90%ethanol extract from the flowers of Hibiscus mutabilis was isolated and purified by various technology,such as silica gel column chromatography,ODS column chromatography and preparative high performance liquid chromatography.The structures of the compounds were identified by the spectral data.Results:Seventeen compounds were isolated and purified from the flowers of Hibiscus mutabilis and identified as honokiol(1),magnolol(2),isohemigossylic acid lactone-2-methyl ether(3),ferulic acid(4),3-indolcarbaldehyde(5),abscisic acid(6),quer-cetin(7),kaempferol(8),8-(1-(3,4-dihydroxyphenyl)ethyl-3,3',4',5,7-pentahydroxyflavone)(9),cyclo-(Pro-Val)(10),benzyl-β-D-glucopyranoside(11),kaempferol-3-O-β-D-glucoside(12),rhodionin(13),quercetin-3-O-(6"-O-trans-coumarayl)-β-D-glucopyrano-side(14),tiliroside(15),kaempferol-3-O-(6"-O-cis-p-coumaroyl)-β-D-glucopyranoside(16),kaempferol-7-O-α-L-rhamnopyranoside(17),respectively.Conclusion:Among them,compounds 1 to 3,5,6,9 to 11,14 are isolated from Hibiscus genus for the first time.

Flowers of Hibiscus mutabilis L.Chemical constituentsIsolation and identification

叶磊、冯丽萍、黄李璐、冯五文、严鑫、胡攀、夏厚林

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成都中医药大学药学院,四川 成都 611137

成都市中草药研究所,四川 成都 610016

木芙蓉花 化学成分 分离鉴定

中国博士后科学基金

2021M690490

2024

中药材
国家食品药品监督管理局,中药材信息中心站

中药材

CSTPCD北大核心
影响因子:0.913
ISSN:1001-4454
年,卷(期):2024.47(1)
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