摘要
目的:考察不同加工方式对延胡索外观性状和内部成分的影响,筛选其合理的产地初加工方法.方法:采用晒干、阴干、冷冻干燥、热风干燥、远红外干燥及微波干燥法处理新鲜延胡索,HPLC法测定原阿片碱、海罂粟碱、延胡索乙素、延胡索甲素、盐酸巴马汀、盐酸小檗碱、去氢紫堇碱含量,色差仪测定粉末颜色,分析复水比、折干率、浸出物及外观性状.化学计量法综合评价各方法对药材品质的影响.结果:晒干延胡索外观性状最佳,生物碱含量较高,但耗时长;热风和远红外干燥耗时缩短,60 ℃干燥外观性状与晒干法接近,生物碱含量较高;微波干燥法耗时最短,生物碱含量最高;阴干法耗时最长,生物碱含量较低,性状差;冷冻干燥药材质轻、内部多孔松泡,生物碱总含量最低.结论:热风60℃干燥法可大幅度提高干燥效率,确保药材性状及成分含量,可用于延胡索规模化产地加工;微波干燥设备改进后应用前景广阔.
Abstract
Objective:To investigate the effect of external characters and internal components contents of Corydalis Rhizoma with different primary processing,and select the appropriate primary processing.Methods:The fresh Corydalis Rhizoma was treated by sun-drying,shade-drying,freeze-drying,hot air drying,far infrared drying and microwave drying methods,and the contents of seven alka-loids,including protopine,glaucine,tetrahydropalmatine,corydaline,palmatine hydrochloride,berberine hydrochloride,dehydrocorydaline were determined by HPLC.The color of powder was determined by color difference meter,the rehydration ratio,drying rate,extract con-tent and external appearance were analyzed.The influence of each method on the quality of medicinal materials was comprehensively evaluated by chemometry.Results:Corydalis Rhizoma treated by sun-drying had the best appearance and higher total alkaloid content,but it took a long time.The dry times of hot air drying and far infrared drying were significantly decreased,and when the temperature was 60 ℃,the appearance was similar to that of sun-drying,and the total alkaloid content was higher.Microwave drying method had the advantages of shortest time,highest total alkaloid content.The shade-drying process took the longest time,with lower total alkaloid con-tent and the poorest appearance.The freeze-dried herbs were light in weight,the internal texture was porous and loose,the content of to-tal alkaloids was lowest.Conclusion;The drying method of hot air at 60 ℃ can greatly improve the drying efficiency,ensure the charac-teristics of medicinal materials and the content of components,and can be used for large-scale processing of Corydalis Rhizoma.The mi-crowave drying has wide development prospects after the equipment improved.
基金项目
陕西省自然科学基金(2023-JC-QN-0996)
陕西省重点研发计划(2020ZDLSF05-09)
陕西省教育厅青年创新团队建设科研计划(21JP030)
国家科技期刊平台
NSTL
万方数据