Distribution of TCM syndrome type of chronic gastritis in children and its relationship with clinical factors
Objective To explore the relationship between TCM syndromes distribution,clinical factors and Helicobacter pylori(HP)infection in children with chronic gastritis.Methods 128 cases of chronic gastritis ad-mitted to the Department of Pediatrics of Tianjin Hospital of Integrated Traditional Chinese and Western Medicine(Tianjin Nankai Hospital)from January 2018 to December 2020 were retrospectively analyzed.Clinical data were collected,TCM syndrome types were determined,and the distribution characteristics of TCM syndrome types and their relationship with clinical factors(gender,age,season of onset,gastroscopy manifestations)and HP infection were analyzed.Results The traditional Chinese medicine syndromes of chronic gastritis in children were spleen and stomach dampness-heat syndrome(43.8%),spleen and stomach weakness syndrome(25.0%),liver and stomach disconcerting syndrome(22.6%),stomach yin deficiency syndrome(5.5%)and stomach stasis syndrome(3.1%).spleen and stomach dampness-heat syndrome can be seen in all age groups and is more common in summer and au-tumn(59.3%and 52.4%,respectively),manifesting more often as erosive gastritis(69.6%).The syndrome of spleen and stomach weakness was more common in school age children(44.8%),winter(44.4%),and superficial gastritis(40.8%).Liver and stomach disconcerting syndrome was more common in adolescent children(35.1%),spring(43.5%),and bile reflux gastritis(48.0%).The distribution of TCM syndromes was correlated with age,season of onset and gastroscopy(P<0.05 or P<0.01).Spleen and stomach dampness-heat syndrome(46.0%)and liver and stomach disconcerting syndrome(25.5%)were higher in HP-positive children than other syndrome types.Spleen and stomach dampness-heat syndrome(36.6%),spleen and stomach weakness syndrome(26.7%)and stomach yin deficiency syndrome(16.7%)accounted for a higher proportion of HP-negative children than other syndrome types,and the difference between groups was statistically significant(P<0.05).Conclusion The distri-bution of TCM syndromes of chronic gastritis in c hildren with different age,season,gastroscopy and HP infection is different.In the process of clinical syndrome differentiation,we should combine multiple factors to improve the accu-racy of syndrome differentiation and improve the therapeutic effect.