Clinical observation on the treatment of 47 cases of cough variant asthma with wind cold attacking lung syndrome in children with Machan Zhike Tang(麻蝉止咳汤)
Objective To observe the clinical efficacy of Machan Zhike Tang(麻蝉止咳汤)in the treatment of wind cold attacking lung syndrome in children with cough variant asthma(CVA).Methods 94 children with CVA wind cold attacking lung syndrome who visited the Pediatric Department of The First Affiliated Hospital of Heilongjiang University of Chinese Medicine from September 2022 to March 2023 were selected.They were randomly divided into a control group and a treatment group,with 47 cases in each group,using a random number table meth-od.The control group received oral treatment with Montelukast sodium chewable tablets,while the treatment group received oral treatment with Machan Zhike Tang.After 14 consecutive days of treatment,the clinical efficacy of both groups was statistically analyzed.The visual analogue scale(VAS)of cough,the Leicester Cough Questionnaire(LCQ)score,exhaled nitric oxide(FeNO),and serum eosinophil(EOS)levels were compared before and after treatment.Results The total effective rate of the control group was 82.98％(39/47),while the total effective rate of the treatment group was 87.23％(41/47).The difference between the two groups was statistically significant(P＜0.05).There was no statistically significant difference in cough VAS score,FeNO count,and serum EOS levels between the two groups before treatment(P＞0.05),indicating comparability.After treatment,the above indicators in both groups significantly decreased,with a statistically significant difference(P＜0.01)compared to before treatment in the same group,and the treatment group showed a more significant decrease(P＜0.05).There was no statistically significant difference(P＞0.05)in the physiological score,psychological score,social score,and total LCQ score be-tween the two groups before treatment,indicating comparability.After treatment,the scores of two or more groups sig-nificantly increased,and compared with the same group before treatment,the difference was statistically significant(P＜0.05),and the treatment group showed a more significant increase(P＜0.05).Conclusion The clinical effica-cy of Machan Zhike Tang in treating CVA with wind cold attacking lung syndrome is definite.It can not only signifi-cantly improve the LCQ score and cough VAS score of children,but also contribute to the recovery of FeNO count and serum EOS level,which is worthy of clinical promotion and application.
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