Objective To observe the clinical efficacy of sequential treatment of pediatric bronchiolitis using traditional Chinese and Western medicine.Methods 66 children with bronchiolitis wind cold closed lung type who were hospitalized in the Pediatric Respiratory Ward of the The First Affiliated Hospital of Henan University of Chi-nese Medicine from October 2018 to October 2019 were selected.They were randomly divided into a treatment group and a control group,with 33 cases in each group,using a random number table method.The control group received nebulized inhalation of budesonide suspension combined with terbutaline suspension during the acute phase,and budesonide suspension(reduced dosage)during the remission phase.On the basis of the treatment method in the control group,the treatment group was given modified Xiaoqinglong Tang(小青龙汤)oral administration in the a-cute phase(wind cold closed lung syndrome),and modified Yupingfeng San(玉屏风散)oral administration in the remission phase(lung spleen qi deficiency syndrome).Both groups were treated continuously for one week during the acute phase,and the efficacy was evaluated after two weeks of continuous treatment during the remission phase.Results After one week of treatment,the total effective rate of the treatment group was 96.97％(32/33),signifi-cantly higher than the control group's 90.91％(30/33).The difference between the two groups was statistically sig-nificant(P＜0.05).Before treatment,there was no statistically significant difference(P＞0.05)in the scores of the main symptoms(asthma,cough,sputum,and wheezing between the two groups)and the secondary symptoms(clear and sparse sputum,nasal congestion,runny nose,pale complexion,poor appetite,loose stools/dry knot be-tween the two groups),indicating comparability.After one week of treatment,the main and secondary symptom scores and total scores of the two groups were significantly reduced compared to the same group before treatment,and the differences were statistically significant(P＜0.01).The main symptom scores and secondary symptom scores of the treatment group were more significantly reduced(P＜0.05 or P＜0.01),while the secondary symptom scores of nasal congestion,pale complexion,poor appetite,and loose/dry stools in the treatment group were not statistically significant compared to the control group(P＞0.05).After recovery period treatment,there was no statistically sig-nificant difference in the total effective rate between the two groups(P＞0.05),but the clinical control rate of the treatment group was 90.91％(30/33),significantly higher than the control group's 39.40％(13/33),with a statis-tically significant difference(P＜0.01).Within one year after discharge,the recurrence rate of wheezing in the treat-ment group was 18.18％(6/33),while in the control group it was 46.88％(15/32).The difference between the two groups was statistically significant(P＜0.05).During the treatment period,there were no abnormalities in blood,urine,stool routine,liver and kidney function and other indicators in both groups of children,and no significant ad-verse reactions occurred.Conclusion The sequential therapy of traditional Chinese and Western medicine for staged treatment of bronchiolitis can significantly alleviate clinical symptoms and signs,significantly reduce tradi-tional Chinese medicine syndrome scores,low recurrence rate,and high safety.It is worthy of clinical promotion and application.
bronchiolitischildrensequential therapy of traditional Chinese and Western medicinestaged treatmentclinical observation
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