Case study of professor HU Siyuan's use of Huolian Baohe Tang(藿连保和汤)in the treatment of pediatric stagnation disease with food accumulation heat syndrome
Objective To observe the therapeutic effect of professor HU Siyuan's use of Huolian Baohe Tang(藿连保和汤)on traditional Chinese medicine syndromes and the improvement of main symptoms in the treatment of pediatric stagnation disease(food accumulation heat syndrome).Methods A retrospective case series study was used to collect a total of 42 cases,treated with Huolian Baohe Tang as the basic formula.One course of treatment las-ted for one week,and after one course,the recovery rate of traditional Chinese medicine syndrome and the recovery rate of traditional Chinese medicine syndrome in each subgroup of age group were statistically analyzed.After one course of treatment,the recovery rates of traditional Chinese medicine syndromes were 51.3％(20/39)and 62.5％(20/32),respectively.9 cases in FAS analysis were ineffective,including 2 cases with no improvement or worsening of follow-up symptoms and a decrease rate of less than 30％in traditional Chinese medicine syndrome scores;Four cases were lost to follow-up.Three cases fails to take medicine on time.The two ineffective cases in PPS analysis on-ly included no improvement or aggravation of follow-up symptoms,and the decrease rate of traditional Chinese medi-cine syndrome score was less than 30％.FAS and PPS analysis showed that the recovery rates of traditional Chinese medicine syndromes in different age groups were 0.0％(0.0％)in the＜1 year old age group,75.0％(3/4)and 75.0％(3/4)in the 1-3 year old age group,52.9％(9/17)and 64.2％(9/14)in the 4-7 year old age group,and 57.1％(8/14)and 66.7％(8/12)in the 8-12 year old age group,respectively.The median score of tradition-al Chinese medicine syndrome was 14(14)before treatment and 4(3)after treatment.After statistical analysis,the difference was statistically significant(P＜0.05).FAS and PPS analysis showed that 15 cases of non lactation disap-peared,with disappearance rates of 38.5％(15/39)and 46.9％(15/32)respectively;21 cases of abdominal dis-tension disappeared,with disappearance rates of 53.8％(21/39)and 65.6％(21/32),respectively.No adverse events or reactions occurred during the observation period.Conclusion Professor HU's use of Huolian Baohe Tang in the treatment of pediatric stagnation disease(food accumulation heat syndrome)can effectively improve the tra-ditional Chinese medicine syndrome and main symptoms of the child,and the therapeutic effect of epigastric disten-sion is better than that of not considering milk food.The results of PPS analysis and FAS analysis are consistent.It is recommended to design prospective case series studies,randomized controlled trials,and other in-depth studies in the future,in order to provide clinical medication ideas for the development of new traditional Chinese medicine.
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