Clinical observation on the adjuvant therapy of modified Huanglong Heji(黄龙合剂)combined with acupoint application in 30 cases of mycoplasma pneumoniae lobar pneumonia of wind heat blocking the lung pattern in children
Objective To observe the clinical efficacy of modified Huanglong Heji(黄龙合剂)combined with acupoint application as adjuvant therapy in children with mycoplasma pneumoniae lobar pneumonia of wind heat blocking the lung pattern.Methods Sixty children with mycoplasma pneumoniae lobar pneumonia of wind heat blocking the lung pattern admitted to the Pediatrics Department of Yixing Traditional Chinese Medicine Hospital from January 2023 to June 2023 were selected and divided into a control group and a treatment group using a ran-dom number table method,with 30 cases in each group.The control group received azithromycin plus cephalosporin therapy and symptomatic treatment such as antipyretic,antiasthmatic,expectorant,and fluid replacement as needed.The treatment group received modified Huanglong Heji combined with acupoint application on the basis of the con-trol group's treatment methods.After 14 days of treatment,the clinical efficacy,disappearance time of symptoms and signs,levels of inflammatory indicators,and incidence of adverse reactions were compared between the two groups.Results The total effectiverate was 93.33％(28/30)in the treatment group and significantly higher at 80.00％(24/30)in the control group,with a statistically significant difference between the two groups(P＜0.05).The time to fever resolution,cough disappearance,and lung shadow absorption were shorter in the treatment group than in the control group,with statistically significant differences between the two groups(P＜0.05).Before treatment,there were no statistically significant differences in the levels of serum C-reactive protein(CRP),procalcitonin(PCT),and heparin-binding protein(HBP)between the two groups(P＞0.05),indicating comparability.After treatment,all the above indicators significantly decreased in both groups compared with before treatment in the same group(P＜0.05),and the decrease was more significant in the treatment group(P＜0.05).During treatment,adverse reactions occurred in 2 cases in the control group(1 case of nausea and vomiting,1 case of mild abdominal pain)and 2 ca-ses in the treatment group(1 case of diarrhea,1 case of rash).There was no statistically significant difference in the incidence of adverse reactions between the two groups(both 6.67％)(P＞0.05).Conclusion Modified Huanglong Heji combined with acupoint application as adjuvant therapy in children with mycoplasma pneumoniae lobar pneu-monia of wind heat blocking the lung pattern can effectively alleviate clinical symptoms,reduce inflammatory re-sponses,and exhibit significant efficacy with good safety,warranting clinical promotion and application.
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