Clinical observation on the adjuvant therapy of Sangqin Huayu Tongluo Tang(桑芩化瘀通络汤)in 40 cases of pediatric mycoplasma pneumoniae pneumonia of phlegm heat obstructing the lung pattern
Objective To observe the clinical efficacy of Sangqin Huayu Tongluo Tang(桑芩化瘀通络汤)as adjuvant therapy in pediatric mycoplasma pneumoniae pneumonia(MPP)of phlegm heat obstructing the lung pat-tern.Methods A total of 80 pediatric patients with MPP of phlegm heat obstructing the lung pattern admitted to the Department of Internal Medicine of No.3 Affiliated Hospital of Nanyang Medical College from May 2022 to May 2023 were selected and divided into a treatment group and a control group using the random number table method,with 40 patients in each group.The control group was treated with Azithromycin Dry Suspension,while the treatment group received Sangqin Huayu Tongluo Tang on the basis of the control group's treatment.After two courses of treatment,the clinical efficacy was evaluated,and comparisons were made between the two groups in terms of tradi-tional Chinese medicine(TCM)syndrome scores,lung function indicators[peak expiratory flow(PEF),forced ex-piratory volume in one second(FEV1),and FEV1/forced vital capacity(FVC)ratio],and serum inflammatory cy-tokine levels[interleukin-6(IL-6),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α),and C-reactive protein(CRP)]before and after treatment.Results The total effective rate in the treatment group was 97.50％(39/40),significantly higher than the 85.00％(34/40)in the control group,with a statistically significant difference between the two groups(P＜0.05).Before treatment,there were no statistically significant differences in PEF,FEV1 and FEV1/FVC levels between the two groups(P＞0.05),indicating comparability.After treatment,all the above indica-tors significantly increased in both groups compared with before treatment,with statistically significant differences(P＜0.05),and the increase was more significant in the treatment group(P＜0.05).Before treatment,there were no statistically significant differences in serum IL-6,IL-8,TNF-α and CRP levels between the two groups(P＞0.05),indicating comparability.After treatment,all the above indicators significantly decreased in both groups compared with before treatment,with statistically significant differences(P＜0.05),and the decrease was more significant in the treatment group(P＜0.05).Conclusion Sangqin Huayu Tongluo Tang as adjuvant therapy for pediatric MPP of phlegm heat obstructing the lung pattern pattern has satisfactory clinical efficacy,effectively alleviating symptoms,improving lung function,and reducing inflammatory responses.It is worthy of clinical promotion and application.
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