An analysis of the characteristics and rules of professor LI Zhijie's medication for treating insomnia based on data mining
Objective:To analyze the medication rule of Professor LI Zhijie in the treatment of insomnia by using data mining technology.Methods:From January 2022 to June 2022,a total of 121 cases of insomnia were collected from the outpatient clinic of the affiliated Hospital of traditional Chinese Medicine of Hubei University of traditional Chinese Medicine.The outpatient database was established by EXCEL software,the association rules of IBM SPSS Modeler 18.0 software was used to mine the common drug combinations,and SPSS Statistic 25.0 was used to analyze 25 high-frequency TCM medicines.Results:A total of 121 prescriptions were included,167 medicine were used,and 25 TCM medicines(high frequency TCM medicines)were used more than 30 times.The top 10 frequently used TCM medicines are Shichangpu(Rhizoma Acori Tatarinowii),Yujin(Radix Curcumae),Yuanzhi(Radix Polygalae),Fushen(Poria cum Radix Pini),Rougui(Cortex Cinnamomi),Huanglian(Rhizoma Coptidis),Fa Banxia(Rhizoma Pinelliae Preparatum),Zhenzhumu(Concha Margaritifera),Shouwuteng(Caulis Polygoni Multiflori)、Longgu(Os Draconis).The distribution of four Qi(气)was mainly flat(727 times),warm(809 times)and cold(751 times).The distribution of five flavors is mainly bitter medicine(1 251 times),meridian distribution is mainly heart meridian(1 269 times)and liver meridian(1 263 times).The efficacy distribution of high-frequency TCM medicine:Calming the liver and suppressing Yang(阳).Followed by relieving cold and relieving pain,warming meridians and dredging meridians,communication heart and kidney.Shichangpu,Huanglian,Yujin and Rougui are the core drugs used in the treatment of insomnia.Four groups of closely related cluster prescriptions were obtained by exercise cluster analysis.Conclusion:LI Zhijie believes that the etiology and pathogenesis of insomnia is based on the disconnection of heart and kidney,phlegm-dampness,liver depression and Qi stagnation as the standard,so the clinical treatment is mainly heart-kidney communication,soothing the liver and relieving depression,resolving dampness and middle.
万方数据
维普
