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不同针刺治疗中风后失眠的网状Meta分析

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目的:系统评价不同针刺治疗中风后失眠的疗效与安全性.方法:计算机检索PubMed、中国知网等中英文数据库,搜集 2010 年-2022 年所发表的针刺治疗中风后失眠的随机对照试验,采用RevMan 5.3、Stata 16.0 软件对纳入的数据进行分析.结果:共纳入 39 篇文献,包括患者 2 551 例,共涉及 9 种针刺方式,分别为常规针刺、耳针、头部督脉排刺、穴位埋线、头针、腕踝针、眼针、针刺联合穴位埋线、针刺联合耳针.网状Meta 分析疗效排序结果显示:①睡眠改善有效率方面,累计概率排名曲线下面积(Surface Under The Cumulative Ranking Curve,SUCRA)累计概率排序为针刺联合穴位埋线>穴位贴敷>头部督脉排刺>腕踝针>头针>耳针>穴位埋线>针刺>针刺联合耳针;②在匹兹堡睡眠指数(Pittsburgh Sleep Quality Index,PSQI)评分方面,SUCRA累计概率排序为针刺+穴位埋线>头部督脉排刺>眼针>针刺>头针.在安全性方面,试验组不良反应/事件的发生率整体少于对照组.结论:9 种针刺方式治疗中风后失眠方面,针刺联合穴位埋线能明显提高中风后失眠的临床疗效,但鉴于不同治疗措施间研究数量与方法学质量存在较大差异,针刺SUCRA累计概率排序结果还有待今后开展多中心、大样本、随机双盲临床对照试验加以验证.
Network Meta-analysis of treating insomnia after stroke by acupuncture
Objective:To systematically evaluate the efficacy and safety of different acupuncture in the treatment of insomnia after stroke.Methods:PubMed,CNKI and other Chinese and English databases were searched by computer to collect the randomized controlled trial of acupuncture in the treatment of insomnia after stroke published from 2010 to March,2022.The included data were analyzed by Revman 5.3 and Stata 16.0 software.Results:A total of 39 literatures were included,including 2 551 patients,involving 9 acupuncture methods,including routine acupuncture,ear acupuncture,head governor vein arrangement acupuncture,acupoint catgut embedding,scalp acupuncture,wrist ankle acupuncture,eye acupuncture,acupuncture combined with acupoint catgut embedding,acupuncture combined with ear acupuncture.The results of net Meta-analysis showed that ① in terms of the effective rate of sleep improvement,the cumulative probability of the area under the surface under the cumulative ranking curve(SUCRA)was acupuncture combined with acupoint catgut embedding>acupoint application>head governor vein arrangement acupuncture>wrist ankle acupuncture>scalp acupuncture>ear acupuncture>acupoint catgut embedding>acupuncture>acupuncture combined with ear acupuncture.② In terms of Pittsburgh sleep index(PSQI)score,the cumulative probability of SUCRA is acupuncture combined acupoint catgut embedding>head governor vein puncture>eye acupuncture>acupuncture>head acupuncture.In terms of safety,the incidence of adverse reactions/events in the experimental group was lower than that in the control group.Conclusion:Acupuncture combined with acupoint catgut embedding can significantly improve the clinical efficacy on post-stroke insomnia.However,in view of the large differences in the number of studies and methodological quality between different treatment measures,the SUCRA cumulative probability ranking results of acupuncture need to be verified by multi center,large sample,randomized double-blind clinical controlled trials in the future.

AcupunctureNetwork Meta-analysisStrokeInsomnia

杨晨晨、邹伟

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黑龙江中医药大学,黑龙江 哈尔滨,150040

黑龙江中医药大学第一附属医院,黑龙江 哈尔滨,150040

针刺 网状Meta 中风 失眠

黑龙江省中医药管理局省级名中医专家传承工作室项目

20190529

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(1)
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