The effect of Buzhong Yiqi decoction on diaphragm function in mechanical ventilation patients with severe pneumonia(lung and spleen Qi deficiency syndrome)
Objective:To study the effect of Buzhong Yiqi decoction(补中益气汤)on diaphragm function in mechanical ventilation pa-tients with severe pneumonia of lung and spleen Qi(气)deficiency syndrome.Methods:A total of 66 patients were randomly divided into the Buzhong Yiqi decoction group and the control group,with 33 cases in each group.The control group was given conventional Western medi-cine treatment,and the Buzhong Yiqi decoction group was given Buzhong Yiqi decoction on the basis of conventional treatment.The course of treatment was 7 days.On the 1st,3rd,5th,and 7th days of treatment,bedside ultrasound was used to measure the degree of diaphragm movement and the thicken-ing rate of diaphragm to evaluate diaphragm function.The offline success rate was calculated.Results:There was no significant difference in diaphragm movement between the two groups on the 1st,3rd,5th and 7th day of treatment.The diaphragmatic muscle thickness in the Buzhong Yiqi decoction group was higher than that in the control group at the end of inspiratory breath on the 5th and 7th days after treatment(P<0.05).There was no significant dif-ference in the thickening rate of diaphragm between two groups on the 1st,3rd and 5th day of treatment.After 7 days of treatment,the thickening rate of diaphragm in Buzhong Yiqi decoction group[(40.87±16.48)%]was higher than that in the control group[(32.49±13.34)%](P<0.05).The APACHE II scores in the two groups were(19.00±6.69)and(17.73±6.02),respectively before treatment,and(11.82±4.51)and(12.45±2.39)after treatment,respectively,and the difference was not statistically significant(P>0.05).The offline success rate was 63.6%in the Buzhong Yiqi decoction group and 51.5%in the control group.The offline success rate in the Buzhong Yiqi decoction group was higher than the control group,and the difference was not statistically significant.Conclusion:Buzhong Yiqi decoction is beneficial to increase the diaphragm thickness and the diaphragm thickening rate at the end of inspiratory breath in patients with severe pneumonia(lung and spleen Qi deficiency syndrome)and improve diaphragm function.
Buzhong Yiqi decoctionSevere pneumoniaMechanical ventilationCritical ultrasoundDiaphragm function
万方数据
维普
