首页|基于数据挖掘的贵州省名中医陈云云治疗绝经前后诸证的学术思想和用药规律分析

基于数据挖掘的贵州省名中医陈云云治疗绝经前后诸证的学术思想和用药规律分析

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目的:基于数据挖掘总结、分析贵州省名中医陈云云教授治疗绝经前后诸证的学术思想和用药规律,传承名老中医学术思想,为中医药治疗绝经前后诸证提供新思路.方法:收集2021年9月―2022年5月贵州中医药大学第二附属医院陈云云教授门诊治疗绝经前后诸证病历,运用现代数据挖掘技术与方法(中医传承辅助平台V2.5)建立处方数据库,对录入处方进行分析,得出用药频次、中药分类,药物四气五味归经、组方规律,提取核心组合与新方,分析陈云云教授治疗绝经前后诸证的用药规律并总结其学术思想.结果:本研究共收集陈云云教授治疗绝经前后诸证病历94份,涉及中药142种,药性以温性、寒性、平性为主;药味以甘、苦、辛三味为主;药物归经以归肝、肾、脾三经为主;以白芍、淫羊藿、巴戟天、当归、茯苓、知母、黄柏、柴胡、熟地黄、仙茅等为核心药物;演化得到10个核心组合,5首新处方.结论:陈云云教授治疗绝经前后诸证主要从补肝肾、调脾胃着手,肝肾亏虚是其主要病因病机,以二仙汤或滋水清肝饮为主方,辨证加以活血药、凉血药、安神药等,各药配伍以达补肝肾、调冲任之功.
An analysis of the academic thought and medication rule of CHEN Yunyun,a famous TCM doctor in Guizhou Province,in the treatment of premenopausal and postmenopausal syndrome based on data mining
Objective:Based on data mining,this paper summarizes and analyzes the academic thoughts and medication rules of Pro-fessor CHEN Yunyun,a famous TCM doctor in Guizhou Province,in the treatment of premenopausal and postmenopausal syndromes,and inherits the academic thoughts of famous veteran TCM doctors,so as to provide new ideas for the treatment of premenopausal and postmenopausal syndromes in traditional Chinese medicine.Methods:By collecting the medical records of Professor CHEN Yunyun for the treatment of various premenopausal and postmenopausal syndromes from September 2021 to May 2022 in the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,the prescription database was established by modern data mining technology and methods(TCM inheritance support system V2.5),and the included prescriptions were analyzed to obtain the frequency of medication,the classification of traditional Chinese medicine,the four properties and five flavors of drugs,the law of prescription,the extraction of core combinations and new prescriptions.The law of medication of Professor CHEN Yunyun for the treatment of various premenopausal and postmenopausal syndromes was analyzed,and the academic thoughts were summarized.Results:In this study,a total of 94 medical records of premenopausal and postmenopausal syndrome treated by Professor CHEN Yunyun were collected,involving 142 kinds of traditional Chinese medicine.The medicinal properties were mainly warm,cold and flat.The flavor of the medicine was mainly sweet,bitter and pungent.The meridian tropism of drugs was mainly based on the three meridians of liver,kidney and spleen,with Baishao(Radix Paeoniae Alba),Yinyanghuo(Herba Epimedii),Bajitian(Radix Morindae Officinalis),Danggui(Radix Angelicae Sinensis),Fuling(Poria),Zhimu(Rhizoma Anemarrhenae),Huangbo(Cortex Phellodendri),Chaihu(Radix Bupleuri),Shudihuang(Radix Rehmanniae Preparata),Xianmao(Rhizoma Curculiginis)as the core drugs.Ten core combinations and five new prescriptions were evolved.Conclusion:Professor CHEN Yunyun's treatment of premenopausal and postmenopausal syndromes mainly starts from tonifying liver and kidney,regulating spleen and stomach.Liver and kidney deficiency is the main etiology and pathogenesis.The main pre-scription is Erxian decoction(二仙汤)or Zishui Qinggan decoction(滋水清肝饮),and blood-activating medicinals,blood-cooling medicinals,sedative medicinals,and so on are added based on syndrome differentiation.The compatibility of each medicinal is performed to obtain the effects of tonifying liver and kidney and regulating Chong and Ren(任冲).

Premenopausal and postmenopausal syndromeData miningAcademic thinkingMedication rule

梁凡、吴青、陈云云、周杰、李尚威

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贵州中医药大学,贵州 贵阳,550025

贵州中医药大学第二附属医院,贵州 贵阳,550001

绝经前后诸证 数据挖掘 学术思想 用药规律

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(3)
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