Medication rules in treating abdominal pain in ancient books of Qing Dynasty based on Chinese Medicine Canon
Objective:To conduct data mining research on the medication of the cases of abdominal pain recorded in ancient books of Qing Dynasty(清代),and analyze the rules of prescription and medication in the treatment of abdominal pain by the doctors of Qing Dynasty,so as to understand the academic thoughts of this period and provide experience for clinical practice.Methods:Taking the fifth edition of Chinese Medicine Canon as the data source,the effective prescriptions for the treatment of abdominal pain in the Qing Dynasty were retrieved and a database was established.The high-frequency drugs,combination rules and core prescriptions for the treatment of abdominal pain were summarized by the association rules,cluster analysis and complex network analysis system contained in the ancient and modern medical records cloud platform(V2.3.5).Results:A total of 196 effective prescriptions were screened,and 202 TCM flavors were used,among which 34 TCM flavors were used more than 10 times including Gancao(Glycyrrhiza uralensis Fisch),Baishao(Radix paeoniae alba),Danggui(Radix angelicae sinensis),Baizhu(Rhizoma macrocephalae),Fuling(Poria Cocos)and Chenpi(Pericarpium citri reticulatae).Four groups of high-frequency drugs were summarized,There were 22 pairs of commonly used associated drug combinations and 1 core prescription.Conclusion:In Qing Dynasty,abdominal pain was mainly treated with deficiency tonifying medicine,internal warming medicine,Qi(气)regulating medicine,etc.The drugs were mainly sweet and warm,the channel of tropism included the spleen and stomach meridians,and the drug pairs such as Houpo(Cortex Magnoliae Officinalis)-Chenpi,Baizhu-Fuling,Chenpi-Baizhu,Fuling-Chenpi,Cangzhu(Rhizoma Atractylodis)-Gancao,and Danggui-Baishao were compatible with each other.Using the methods of warming and tonifying deficiency,regulating Qi and invigorating the spleen,clearing heat and detoxifying,removing dampness and expelling phlegm,nourishing blood and harmonizing blood,soothing liver and relieving the acute symptoms,etc.,methods of taking the methods of clearing,warming and tonifying of cluster analysis as the main treatment,and starting from the three major syndromes of Spleen and stomach deficiency cold syndrome,Phlegm-dampness stagnation syndrome,and Qi and blood disharmony syndrome,a new prescription is obtained,the prescription and the characteristics of medication in the treatment of abdominal pain in Qing Dynasty are discussed,and the ideological characteristics of this period is understood,which also provides a new way of thinking for the treatment of abdominal pain in TCM in modern timess.
Abdominal painChinese Medicine CanonData miningMedication ruleAncient and modern medical records cloud platform