Data mining on the medication law of Professor ZHOU Mingxin in the treatment of eczema based on prescription metrology
Objective:To study the medical record prescriptions of Professor ZHOU Mingxin for the diagnosis and treatment of eczema by applying"prescription metrology"research method created by Professor ZHOU,and excavate the scope of medication,drug composition and prescription rules,so as to summarize the compatibility rules of prescription composition and clinical application rules.Methods:A totalof 50 effective cases of eczema treated by Professor ZHOU Mingxin from January 2018 to June 2021 were screened.The name,property,channel tropism and category of the drugs used were statistically analyzed,and the data was systematically clustered by statistical software package SPSS 26.0.Results:Professor ZHOU Mingxin used 96 drugs in the treatment of eczema,with a frequency of 592 times;The medicine was mainly cold,warm,mild and slightly cold,and the medicine property was mainly bitter,pungent and sweet;The main channel tropism of medication was liver channel,which was followed by lung,stomach,spleen,heart channels;The drugs used were mainly heat clearing and dampness drying drugs,wind cooling drugs,wind dampness removing drugs,diuretics and drenching drugs,heart nourishing and tranquilizing drugs,dampness removing drugs,wind heat dispersing drugs,wind calming and antispasmodic drugs;Commonly used drugs were:Baixianpi(Dictamni Cortex),Wushaoshe(Zaocys),Difuz i(Fructus rehmanniae),Jingjie(Schizonepeta tenuifolia),Tianma(Gastrodia elata),Fuping(Duckweed),Suanzaoren(Seed of wild jujube),Cangzhu(Atractylodes rhizome),Fangfeng(Radix Angelicae dahuricae),Baizhi(Radix angelicae),Kushen(Rdix sophorae flavescentis),Chantui(Cicada slough),Zhizi(Fructus Gardeniae),Chonglou(Rhizoma Paridis),Hehuanpi(Cortex Albiziae),Longgu(Keel),Muli(Oyster),Sharen(Amomum villosum),Baishao(White peony),Baizhu(Atractylodes macrocephala),Huangbo(Cortex Phellodendri),Huanglian(Rhizoma Coptidis),Huangqin(Scutellaria baicalensis),Fuling(Poria cocos),Tufuling(Smilax glabra),Danggui(Angelica),Huangqi(Astragalus),Jiezi(Sinapis semina),Qianghuo(Notopterygium),Shouwuteng(Polygonum multiflorum),Xiyangshen(American ginseng),etc;The drugs for this syndrome were Baixianpi,Wushaoshe,Difuzi,Jingjie,and Tianma Unit drug groups included 4 groups of couplet drugs and 2 groups of triple compatible drugs.Conclusion:Professor ZHOU Mingxin's academic experience in treating eczema with"wind-dampness stagnation hinders the muscle and defensive Qi(气)"as the"pathogenesis of the disease"and"dispelling wind,drying dampness and dispersing defensive Qi"as the method has outstanding characteristics and exact curative effects,which is worthy of reference and promotion.