The diagnosis and treatment regularity of acute icterus hepatitis in Series Books of Hunderd TCM Clinical Experts of the Century based on data mining analysis
Objective:To analyze the medication rules of acute icterus hepatitis treated by hundreds of famous TCM practitioners in modern China by data mining technology.Methods:The prescriptions for treating acute icterus hepatitis in Series Books of Hunderd TCM Clinical Experts of the Century(1st edition)were collected to screen out the prescriptions that met the inclusion criteria.The included prescriptions were uploaded to the traditional Chinese Medicine inheritance support system V2.5,and the database was established.Frequency analysis,cluster analysis,association rules and other data mining techniques and methods were used to analyze the included prescriptions.Results:Based on the analysis of 200 initial and re-diagnosis prescriptions,it was concluded that the commonly used drugs for treating acute icterus hepatitis by hundreds of TCM practitioners in modern times were Yinchen(Herba Artemisiae Scopariae),Zhizi(Fructus Gardeniae),Gancao(Radix Glycyrrhizae),Fuling(Poria),Yujin(Radix Curcumae),etc..The high-frequency drug combinations included Zhizi-Yinchen,Yujin-Yinchen,Dahuang(Radix et Rhizoma Rhei)-Yinchen,Fuling-Yinchen,Zexie(Rhizoma Alismatis)-Yinchen,etc..The new prescriptions included Zhuru(Caulis Bambusae in Taenia)-Fuling-Shichangpu(Rhizoma Acori Tatarinowii)-Banxia(Rhizoma Pinelliae)-Chenpi(Pericarpium Citri Reticulatae),Baimaogen(Rhizoma Imperatae)-Chishao(Radix Paeoniae Rubra)-Huanglian(Rhizoma Coptidis)-Sangbaipi(Cortex Mori),Shenqu(Massa Fermentata)-Baidoukou(Fructus Amomi Rotundus)-Foshou(Fructus Citri Sarcodactylis)-Maiya(Fructus Hordei Germinatus)-Meiguihua(Flos Rosae Rugosae),Yinchen-Dahuang-Zhizi-Danggui(Radix Angelicae Sinensis),Qingdai(Indigo Naturalis)-Gouqizi(Fructus Lycii)-Chuipencao(Herba Sedi Sarmentosi)-Baijiangcao(Herba Patriniae)-Jianghuang(Rhizoma Curcumae Longae),etc..Conclusion:Based on the traditional Chinese medicine inheritance support system,using data mining technology,it is found that the treatment of acute icterus hepatitis by hundreds of TCM practitioners in modern times follows the treatment principle of removing dampness and relieving acute icterus hepatitis,which reflects the academic thought of eliminating dampability and promoting urine in the treatment of acute icterus hepatitis,and conforms to the medication principle of treating both symptoms and root causes of TCM.