Application of the Dachaihu decoction in treating postembolization syndrome after transarterial chemoembolization of liver cancer
Transarterial chemoembolization(TACE)is one of the most commonly used methods for non-surgical treatment of liver cancer.Postembolization syndrome(PES)is a common complication of TACE for primary liver cancer,the main symptoms were postoperative fever,pain,nausea and vomiting,constipation,liver function damage,and so on.At present,there is no specific treatment in western medicine,mainly symptomatic support treatment.Professor FANG Wenyan,the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,has worked for more than 30 years,especially good at integrated traditional Chinese and western medicine in the treatment of advanced malignant tumors and their complications.He has experience in the interventional treatment of liver cancer and the clinical management of PES after TACE,and is well received by patients.The patients with liver cancer complicated with PES after TACE have different physique and syndrome types.We should follow the principle of knowing what is wrong and following syndrome and treatment and make a flexible prescription based on syndrome differentiation.Professor FANG believes that the occurrence of liver cancer is the final result of long-term slow pathological changes with stagnation of liver Qi(气)as the core,and that the syndrome of stagnation of liver Qi and stagnation of damp-heat in the interior is one of the common syndromes of PES in patients after TACE.The Dachaihu decoction(大柴胡汤)comes from Shanghan Lun(《伤寒论》),which can be treated with harmonizing Shaoyang(少阳),purging heat,and simultaneous treating Qi and blood.Professor FANG believes that liver cancer is based on liver depression and Qi stagnation,and patients often have clinical manifestations of stagnation of liver collaterals and lack of internal defense.It is a disease of asthenia in origin and asthenia in superficiality.The effect on PES of liver stasis and Qi stagnation and damp-heat internal obstruction after TACE of liver cancer with the Dachaihu decoction is remarkable.This paper makes a trial analysis of FANG's thought of clinical application,together with an experimental case,in order to provide theoretical reference for the application of TCM medicine in the treatment of malignant tumors.
The Dachaihu decoctionLiver cancerTransarterial chemoembolizationPostembolization syndrome
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