Discussion on the rule of treating chronic non-atrophic gastritis of the damp heat of spleen and stomach type in TCM based on data mining
Objective:To explore and analyze the medication rule of treating chronic non-atrophic gastritis of the damp heat of spleen and stomach type in TCM based on data mining.Methods:In CNKI and Wanfang data,the prescriptions of TCM medicine for the treatment of chronic non-atrophic gastritis of the damp heat in the spleen and the stomach type from the establishment of the database to September 1,2022 were collected and screened and introduced into Traditional Chinese Medicine Inheritance Computing Platform V3.0.The frequency of use,four Qi(气)and five flavors,meridian properties,channels tropism and efficacy of the drugs in the prescription are analyzed.Association rules and k-means clustering algorithm are used for calculus analysis.Results:A total of 91 effective prescriptions were collected,involving 112 TCM medicines.The frequency of single medicine is the highest in Huanglian(Rhizoma Coptidis),followed by Banxia(Rhizoma Pinelliae).The main medicinal properties are cold and warm,followed by neutral.The bitter and pungent taste of the medicine is the heaviest,supplemented by sweet taste.The spleen channel and stomach channel are the main channels,followed by the lung channel.The main functions are heat-clearing drugs,deficiency-tonifying drugs,dampness-resolving drugs and Qi-regulating drugs.The top six commonly used drug combinations are Huanglian-Banxia,Huanglian-Chenpi(Pericarpium Citri Reticulatae),Banxia-Houpo(Cortex Magnoliae Officinali),Banxia-Huangqin(Radix Scutellariae),Huanglian-Huangqin,Banxia-Chenpi.Three pairs of core drug combinations were obtained by k-means clustering,which were Huanglian-Banxia-Chenpi-Huangqin-Houpo,Houpo-Banxia-Huanglian-Huangqin-Gancao(Radix Glycyrrhizae),Huanglian-Banxia-Shengjiang(Rhizoma Zingiberis Recens)-Houpo-Cangzhu(Rhizoma Atractylodis).Conclusion:TCM treatment of chronic non-atrophic gastritis of the damp heat of spleen and stomach type should be based on the principles of clearing heat,dispelling dampness,regulating Qi and middle-jiao(中焦).Take acrid-bitter herb as the important guiding ideology.The main purpose is to restore ascending or descending movement of vital Qi.Take the Banxia Xiexin decoction(半夏泻心汤)and WANG's Lianpo Yin(王氏连朴饮)as the basic prescription for treatment.This prescription can not only reduce the level of inflammation,inhibit gastric acid secretion,promote the repair of gastric mucosa,but also improve gastrointestinal motility,reduce clinical symptoms and improve prognosis.
Data miningThe damp heat of spleen and stomach typeChronic non-atrophic gastritisChronic superficial gastritis
万方数据
维普
