A mechanism analysis of the application of treating immunoglobulin A nephropathy with the Shenfeng decoction
Immunoglobin A nephropathy(IgAN)is one of the most common primary glomerular diseases,and this article will discuss Professor HE Xuehong's ideas for the treatment of IgAN from the perspective of Weiqi Yingxue(卫气营血)syndrome differentiation and the idea of adapt to the situation.Teacher HE believes that the disease is similar to the warm disease,with wind heat and damp heat as the main body,with wind as the forerunner,and wind heat is the first to invade the human body to form the Weifen syndrome(卫分证),which is wet and viscous,and it is difficult to distinguish between damp and heat,resulting in the prolongation of the disease.The pathogenesis process is similar to that of Weiqi Yingxue,which is mostly induced by external sense,and the early stage is mainly manifested by the Weifen syndrome,followed by edema,oliguria,foamy urine and other the Qifen syndrome(气分证)manifestations,evil Qi(气)can also directly enter the blood without Qifen,and macroscopic hematuria appears at the same time as external sensation.In terms of treatment,master HE used the idea of adapt to the situation,combined with the syndrome differentiation theory of Weiqi Yingxue,and applied the formula the Shenfeng decoction(肾风汤)to clinical practice.The idea of the Shenfeng decoction is elaborated as follows:firstly,follow the trend of the disease to guide the evil to go out,for the wind heat above,the application of Fangfeng(Radix Saposhnikoviae),Jingjietan(Herba Schizonepetae),the trend of the wind and the clear trend of the wind and penetrate the outside,for the damp heat below,the application of Lugen(Rhizoma Phragmitis),Baimaogen(Rhizoma Imperatae),along the trend of the dampness and infiltration of the downward,secondly,to follow the trend of the human body and protect the right guide,the use of small doses of Huangqin(Radix Scutellariae),Chuanlianzi(Fructus Toosendan)to clear heat and protect Jin(津),the Yin(阴)and protect the Yang(阳),the application of Danshen(Radix et Rhizoma Salviae Miltiorrhizae),Qiancao(Radix Rubiae),Jinyinhua(Flos Lonicerae Japonicae),Xuantong Qi movement(宣通气机),diathermy and Zhuanqi(转气),at the same time to be vigilant against disease transmission,the application of Diyv(Radix Sanguisorbae),Huaihua(Flos Sophorae),Xiaoji(Herba Cirsii),Shuihonghuazi(Fructus Polygoni Orientalis),Dahuang(Radix et Rhizoma Rhei),Danshen cools blood and disperses blood to prevent stasis,and finally in terms of diet and daily life,it should also follow the natural trend to prevent and recuperate.Teacher HE often uses the Shenfeng decoction as the base prescription and adjusts the medication according to the patient's clinical manifestations and tongue and pulse dialectic,and has achieved great results in clinical treatment.
Immunoglobulin A nephropathyThe Weiqi Yingxue syndrome differentiationAdapt to the situationThe Shenfeng decoctionWind heatDamp heat