首页|基于升清降浊理论从脾胃论治高尿酸血症

基于升清降浊理论从脾胃论治高尿酸血症

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高尿酸血症是一种以血尿酸升高为特征的代谢性疾病,临床上大部分患者处于无症状的亚健康状态,少数人可因尿酸盐沉积在关节或肾脏引起痛风.中医认为,高尿酸血症可归属为"血浊"的范畴,系本虚标实之证,核心病机为脾胃升清降浊功能失常,痰湿瘀浊阻滞脉道,浊毒内蕴.临床治疗以固本祛邪、复常升降为基本思路,以升清降浊、通利气机为为基本法则,固护脾胃,恢复其升清降浊之功,贯穿治疗始终.同时在高尿酸血症发病的不同阶段分期论治,灵活加减用药.无症状期予以运脾化湿,注重气化;急性期予以清热利湿,祛瘀泄浊;慢性期(间歇期)治以健脾补肾,化瘀通络.临床辨证施治时,药味甘苦辛并用,归经以脾胃为主,升清降浊,气血同调,尤其重视恢复人体气机通畅;祛瘀渗湿,导浊邪下泄;健脾补肾,调理五脏.临证时注重辨病与辨证相结合,调补脾胃,复其升降为主,选方用药时尤重健运脾胃,复脾胃枢机之功,升清阳降浊阴,擅用土茯苓与萆薢、薏苡仁与苍术、荷叶与山楂、车前草与玉米须、川芎与丹参等药对,体现了固本祛邪、升降相因、气血兼顾的用药特点,使气机通畅,清升浊降,恢复血液清净纯和的状态.笔者在临床上发现,基于升清降浊理论从脾胃论治高尿酸血症在降低患者血尿酸及改善症状上显示出了较好的疗效.
Exploration on treating hyperuricemia from the spleen and stomach based on the theory of ascending and lowering turbidity
Hyperuricemia is a metabolic disease characterized by elevated blood uric acid,clinically most patients are in asymptomatic sub-healthy state,a few people can be caused by urate deposition in the joints or kidneys causing gout.According to TCM,hyperuricemia can be attributed to the category of Xuezhuo(血浊),which is evidence of deficiency and solidity,and the core pathology is the malfunction of the spleen and stomach in elevating and lowering the turbidity,and the blockage of veins by phlegm,dampness,stasis and turbidity,and the accumulation of turbidity and toxins within the body.Clinical treatment is based on the basic idea of solidifying the root of the disease,eliminating evils and restoring normal lifting and lowering,and the basic rule of ascending clearness and lowering turbidity and facilitating the flow of Qi(气)is to solidify and protect the spleen and stomach,and to restore the function of ascending clearness and lowering turbidity,which will be carried out throughout the treatment.At the same time,the treatment is staged at different stages of the onset of hyperuricemia,with flexible addition and subtraction of drugs.In the asymptomatic stage,it is used to transport the spleen and eliminate dampness,focusing on Qi.In the acute stage,it is used to clear away heat and relieve dampness,remove blood stasis and drain turbidity.In the chronic stage,it is used to strengthen the spleen and tonify the kidneys,and eliminate blood stasis and clear the channels.In clinical diagnosis and treatment,sweet,bitter and pungent flavors of medicines are used,and the attributing meridian is based on the spleen and stomach,so as to elevate clearness and lower turbidity,and to regulate Qi and blood,with special emphasis on restoring the body's Qi to be smooth,eliminating blood stasis and seeping away dampness and directing the drainage of turbid evils,strengthening the spleen and tonifying the kidneys,and regulating the five viscera.The combination of disease identification and evidence identification,tonifying the spleen and stomach,and restoring its elevation are the main focuses of the prescription and medication,especially in strengthening the spleen and stomach,restoring the spleen and stomach pivotal function,ascending the clear Yang(阳)and descending the turbid Yin(阴),and making use of Tufuling(Rhizoma Smilacis Glabrae)-Bixie(Rhizoma Dioscoreae Hypoglaucae),Yiyiren(Semen Coicis)-Cangzhu(Rhizoma Atractylodis),Heye(Folium Nelumbinis)-Shanzha(Fructus Crataegi),Cheqiancao(Herba Plantaginis)-Yumixu(Stigma Maydis),Chuanxiong(Rhizoma Chuanxiong)-Danshen(Radix et Rhizoma Salviae Miltiorrhizae)pairs of drugs,which embodies the characteristics of solidifying the root of the body to eliminate the evils,elevating and descending the same cause,and taking into consideration the characteristics of the medicines of Qi and blood,so as to enable the Qi and energy to flow smoothly,and to raise the turbidity and lower the turbidity and blood to restore its state of purity and purity is restored.The author found in the clinic that it showed good efficacy in reducing patients'blood uric acid and improving symptoms.

HyperuricemiaSpleen and stomachAscending and lowering turbidityTCM treatment

黄金娟、邓奕辉

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湖南中医药大学第一附属医院,湖南 长沙,410007

湖南中医药大学,湖南 长沙,410007

高尿酸血症 脾胃 升清降浊 中医药治疗

国家重点研发计划国家重点研发计划湖南省科技创新团队项目(2020)

2022YFC35012002022YFC35012022020RC4050

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(5)
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