Efficacy and safety evaluation of moxibustion in the treatment of chronic prostatitis/chronic pelvic pain syndrome:a systematic review and Meta-analysis
Background:The incidence of chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)is increasing with the change of Modern lifestyle and the aggravation of the aging society.At present,western medicine is mainly used for treatment,however,there are some adverse reactions and complications.Moxibustion on CP/CPPS has a good effect,but there is a lack of evidence-based evidence.Objective:To systematically evaluate the efficacy and safety of moxibustion in the treatment of CP/CPPS.Methods:According to the search strategy,Cochrane Clinical Controlled Trial Center Registry,Pubmed,Embase,China Biomedical Literature Database,CNKI,VIP Chinese Scientific and Technological Joumal Database,Wanfang Database and other relevant databases were searched from the establishment of each database to April 1,2022.RCT literature on moxibustion in the treatment of CP/CPPS was screened,and the main outcome indicators were clinical effective rate,NIHI-CPSI score,NRS score,QOL score,UD score,WBC.The quality of the included literature was evaluated according to the Cochrane handbook.Review Manager 5.4 and Stata 16.0 were used to analyze the data.Results:Fifteen articles were included,including 1 301 patients.The clinical effective rate in the test group[RR=1.22,95％CI(1.16,1.30),P＜0.000 01]was higher than the control group.NIH-CPSI score[MD=1.55,95％CI(-2.15,5.25),P＜0.000 1],NRS score[MD=-0.01,95％CI(-2.37,2.34),P＜0.000 1],QOL score[MD=0.12,95％CI(-3.58,3.83),P=0.95],NRS score[MD=-0.01,95％CI(-2.37,2.34),P=0.95],UD score[MD=-1.07,95％CI(-1.42,0.71),P＜0.000 1],WBC[MD=2.79,95％CI(1.28,4.30),P＜0.000 1]in the test group were lower than those in the control group.Subgroup analysis of clinical effective rate and NIH-CPSI score showed that the clinical effective rate was higher than that in the control group[RR=1.20,95％CI(1.13,1.28),P＜0.000 01);RR=1.33,95％CI(1.56,1.53),P＜0.000 1].TheNIH-CPSI scores were lower than the control group[MD=0.47,95％CI(-1.46,2.39),P＜0.000 1;MD=7.69,95％CI(-1.22,16.50),P＜0.000 1].Conclusion:Moxibustion on CP/CPPS has good clinical effica-cy and safety,but more high-quality clinical studies are needed to confirm the conclusion.
万方数据
维普
