An analysis of medication law of Director HU Xin in the TCM maintenance treatment of breast cancer based on data mining
Objective:To summarize the medication law of Director HU Xin in the treatment of breast cancer by TCM maintenance.Methods:A total of 102 outpatient prescriptions of Director HU Xin in the treatment of breast cancer by TCM maintenance from January 2019 to December 2021 were collected and screened.Then they were input into TCM inheritance computing platform(V3.0),and frequency statistics,association rules and other methods were used to carry out statistics and analysis.Results:(1)Herb frequency analysis:The 102 prescriptions involved 133 Chinese medicinal materials.There were 18 Chinese medicinal materials flavors of herbs with a frequency of 40 times or more.The top 10 herbs used frequently were Shanyao(Yam),Hujisheng(Mistletoe),Xiakucao(Prunella Vulgaris),Dangshen(Codonopsis pilosula),Zhebeimu(Fritillaria thunbergia),Shancigu(Mountain arrowhead),Yiyiren(Coix seed),Hongjingtian(Rhodiola),Gancao(Licorice)and Fuling(Poria).(2)Medicinal properties,flavors,and meridians:Mild drugs had the highest frequency of use,reaching 724 times,accounting for 42.12%.The main flavors were sweet and bitter,accounting for 45.12%and 30.76%,respectively.The active ingredients of Chinese medicinal materials mainly flow into the lung and spleen meridians,followed by the stomach,liver,heart,and kidney meridians.(3)Analysis of prescription rules:There were 67 medicine combinations,including 13 Chinese medicinal.The frequency of medicine combinations from high to low was as follows:Shanyao-Hujisheng,Shanyao-Yiyiren,Shanyao-Shancigu,Shanyao-Xiakucao,Xiakucao-Zhebeimu,etc.There were 30 medicine association rules,and the combinations with higher correlation were Yiyiren-Hongjingtian-Shanyao,Hujisheng-Yiyiren-Shanyao,Xiakucao-Yiyiren-Shanyao,Zhuru(Caulis Bambusae in Taenia)-Shanyao,Zhebeimu-Yiyiren-Shanyao,etc.Conclusion:Director HU Xin emphasizes the pathogenesis of"deficiency in origin and excess in superficiality"in the breast cancer by TCM maintenance treatment,and clinically adopts the treatment idea of"supplementing the spleen,nourishing the stomach and supplementing the lung to target the root causes,and clearing heat,resolving phlegm and dispersing knot to relieve the symptoms".It has reference significance for clinical maintenance treatment of breast cancer in TCM.
Breast cancerTCM inheritance computing platformMedication law