Analysis of depression syndrome distribution and medication rules based on the literature
Objective:To explore the depression syndrome distribution and medication rules in TCM treatment by using the method of bibliometric analysis.Methods:With"Theme"as the search term,"Depression","Syndrome type","Syndrome ele-ments","TCM"and"Chinese medicine"as the search words,the literature related to TCM treatment of depression from June 30,2011 to June 30,2022 was searched in three Chinese databases:CNKI,VIP and Wanfang.WPS software was used to establish the overall syndrome type and clinical drug database of TCM treatment of depression,Excel was used for frequency analysis,and SPSS23.0 software was used for cluster analysis.Results:A total of 127 literatures meeting the criteria were included.There were 67 types of syn-drome involved.There were 7 elements of disease location and 14 pathogenic factors involved.There were 215 prescriptions involved,17 types of drugs,160 flavors of drugs were used,with a total frequency of 2,619 times.① There were 67 types of syndrome involved,among which the common types were liver-qi stagnation syndrome,liver-qi spleen deficiency syndrome and heart-spleen deficiency syndrome,accounting for 41.05%.② In terms of elements of disease location involved,the liver was predominant,which was followed by the spleen and heart.In terms of pathogenic elements,Qi(气)stagnation was predominant,which was followed by Qi deficiency and Yang(阳)deficiency.③ The total number of Chinese medicine involved was 160 flavors,which were divided into 17 categories according to their ef-ficacy,with deficiency tonifying drugs accounting for 28.75%,tranquilizing drugs accounting for 11.76%,and Qi-regulating drugs account-ing for 11.53%.④ The medicinal properties of traditional Chinese medicine used in the treatment of depression were mainly warm and mild,the taste of medicine was mainly sweet,bitter and pungent,and the spleen meridian was mainly used in the treatment of depression.Conclusion:The etiology and pathogenesis of depression are complex,which is mostly mixed with deficiency and excess,the pathogenic factors are mainly Qi stagnation,Yang deficiency and Qi deficiency,and the elements of disease location are dominated by the liver,but from the analysis of the medication rules in clinical treatment,it can be seen that the clinical treatment of depression is dominated by the supplementation of deficiency,and the attribution of meridian to spleen meridian is dominated.
DepressionSyndrome elementsSyndrome typeMedication ruleLiterature research