Discussion on the syndrome differentiation and treatment of diabetes-related sarcopenia based on Yin-fire theory
LI Gao,one of the Four Great Physicians of the Jin-Yuan Dynasty,put forward the theory of Yin-fire(阴火),which centers on the fact that when the spleen and stomach Qi(气)are injured,there is an abnormality of ascension and despondency;when the vital Qi is not full,there is an exuberance of Yin-fire within the body,which is more compatible with the pathogenesis of diabetes-related sarcopenia.Qi deficiency is closely related to Yin-fire,and the deficiency of spleen and stomach Qi plays an important role in the formation of Yin-fire.Diabetes-related sarcopenia is a diabetic complication associated with elevated blood glucose and characterized by a decrease in skeletal muscle mass and muscle strength or somatic function,which is similar to the manifestation of Yin-fire in TCM.Based on the theory of Yin-fire,we analyze the pathogenesis and treatment of diabetes-related sarcopenia from the perspective of TCM,and conclude that the deficiency of vital energy is the basis for the occurrence of diabetes-related sarcopenia,and the imbalance of Qi and fire is the etiology for the development of diabetes-related sarcopenia.The relationship between Yin-fire and the pathogenesis of diabetes-related sarcopenia is discussed,and the theory of Yin-fire is applied to prevent and treat diabetes-related sarcopenia.Diabetes-related sarcopenia belongs to the category of Xiaoke(消渴)associated with Wei syndrome(痿证)in TCM,and its intrinsic pathogenesis is the deficiency of vital energy and the internal blazing of Yin-fire.Diabetes-related sarcopenia is caused by the prolonged involvement of bone,flesh,muscle and veins due to Xiaoke,which is in line with LI Gao's theory of Yin-fire.From the overall concept of TCM,the treatment is based on tonifying the spleen and stomach,elevating the clear Yang(阳),and diarrhea of Yin-fire,the methods of clearing heat with sweet-warm medicines,and elevating the Yang and purging fire run through the whole process of the treatment of this disease,which is aimed at further improving the TCM theories of diabetes-related sarcopenia,and thus providing the theoretical basis for the clinical diagnosis and treatment of diabetes-related sarcopenia.
Yin-fireDiabetes-related sarcopeniaXiaokeWei syndromeCharacteristics of syndrome differentiation and treatment