An analysis of medication regularity of granulomatous lobular mastitis in mass stage based on data mining
Objective:To explore the medication regularity and compatibility of TCM medicine in the treatment of granulomatous lobular mastitis in the literature based on the method of data mining.Methods:The papers about the treatment of granulomatous lobular mastitis with TCM medicine from 1980 to 2022 in CNKI,Wanfang data,VIP periodical resource integration service platform and Chinese biomedical literature database were searched by computer,and the studies that met the inclusion criteria were strictly screened.The standardized prescription database of granulomatous lobular mastitis in mass stage was established by Excel.The efficacy category and meridian tropism of TCM medicine were analyzed by the method of data mining,association rule analysis and systematic cluster analysis.Results:A total of 47 compound prescriptions of TCM medicine were included,involving 111 kinds of TCM medicine,and the cumulative use frequency of medicine was 574.The medicine with higher frequency included Chaihu(Radix Bupleuri),Zaojiaoci(Spina Gleditsiae),Baijiezi(Semen Brassicae),Pugongying(Herba Taraxaci),Shudihuang(Radix Rehmanniae Preparata)and so on.The commonly used efficacy categories of TCM medicine were regulating Qi(气)and resolving phlegm,most of the four Qi were cold and warm,and most of the five flavors were bitter and pungent,and the top three meridians were liver,spleen and stomach meridians.Through the analysis of association rules,it was concluded that there were 16 groups of potential compatibility combinations,which were the addition and subtraction combinations of Baijiezi,Mahuang(Herba Ephedrae),Shudihuang,Paojiang(Rhizoma Zingiberis Preparatum),Rougui(Cortex Cinnamomi)and Xiangfu(Rhizoma Cyperi).Five core groups were excavated by cluster analysis.Conclusion:The method of warming Yang(阳),regulating Qi and resolving phlegm is often used in the TCM treatment of granulomatous lobular mastitis.
万方数据
维普
