The Guizhi Gegen decoction plus Liuwei Dihuang pills combined with etanercep injection on 42 cases of ankylosing spondylitis of kidney deficiency and Du-meridian cold type
Objective:To observe the curative effect of the Guizhi plus Gegen decoction(桂枝加葛根汤),Liuwei Dihuang Wan(六味地黄丸)and etanercept on ankylosing spondylitis of kidney deficiency and Du-meridian(督)cold type.Methods:The patients with ankylosing spondylitis of kidney deficiency and Du-meridian cold type diagnosed and treated in the Rheumatology Department of the Matang Hospital of Traditional Chinese Medicine in Xianning,Hubei Province,were divided into two groups by random number table method and combined with the wishes of the patients.The control group(40 cases)was treated with etanercept.The observation group(40 cases)was treated with the Guizhi plus Gegen decoction,Liuwei Dihuang Wan and etanercept.The course of treatment was 3 months.BASFI score,VAS score,BASMI score and other indexes were evaluated before and after treatment.Results:The therapeutic indexes and the amelioration extent of disease in the observation group were better than those in the control group(P<0.05).The total effective rate was higher than that in the control group(P<0.05).Conclusion:Etanercept has a significant therapeutic effect.The Guizhi plus Gegen decoction combined with the Liuwei Dihuang Wan and etanercept have better therapeutic effects on ankylosing spondylitis of kidney deficiency and Du-meliorate cold type.The combination of TCM and Western medicine is beneficial to ameliorate the clinical manifestations of the patient,such as aversion to cold and fatigue,and to improve the patient's sense of well-being.
The Guizhi plus Gegen decoctionLiuwei Dihuang WanEtanerceptAnkylosing spondylitis