Exploring the rules of medication in treating cough based on Professor SHI Qiang's thought of reducing excess and regulating Qi
Objective:To explore the medication rule of Professor SHI Qiang in treating cough,so as to provide useful reference for the clinical diagnosis and treatment of cough.Methods:A total of 275 effective prescriptions for the treatment of cough by Professor SHI Qiang were collected.After drug standardization,Excel 2021 was used to classify the frequency,four Qi(气),five flavors,meridian tropism,toxicity and efficacy of the traditional Chinese medicines.IBM SPSS Statistics 26.0 was used to carry out systematic R clustering of high-frequency traditional Chinese medicines(frequency>10％),and combined with professional knowledge to select predictive classification.The factor analysis(principal component analysis)of SPSS Statistics 26.0 was used to carry out Kaiser-Meyer-Olkin(KMO)and Bartlett spherical test for high frequency traditional Chinese medicines(frequency>10％),and the distribution of common factors was extracted according to the results.Results:A total of 245 traditional Chinese medicines were used in 275 prescriptions,with a cumulative frequency of 3 388 times.Frequency analysis shows a total of 38 traditional Chinese medicines with frequency>10％,including Chuanbeimu(Bulbus Fritillariae Cirrhosae),Chantui(Periostracum Cicadae),Shigao(Gypsum Fibrosum),Kuxingren(Semen armeniacae amarum),Wushaoshe(Zaocys),etc..The medicinal properties are mainly cold and warm,the flavors are mostly sweet,bitter and pungent,and the kinds of meridian tropism are mainly lung,stomach,spleen and liver meridians.The efficacy classifications in descending order of relieving phlegm cough and asthma medicines,heat-clearing medicines,relieving superficies medicines and dissolving retained fluid medicines,etc..The high-frequency drugs(frequency>10％)is divided into 10 categories by cluster analysis,and the factor analysis yields 14 common factors.Conclusion:Different core drugs under the Yangming(阳明)wind-heat superficies syndrome,upper energizer(Fu-organ)dampness-phlegm obstruction,improper ascending and descending,and Yingfen(营分)wind-heat syndrome were analyzed from the clinical cough effective prescriptions.It reflects Professor SHI Qiang's medication ideas of using the theory of mutual exterior-interior relation between lung and large intestine,the theory of separate treatment of phlegm and drink,the theory of ascending and descending of Qi movement,and the mechanism of wind evil based on the thought of reducing excess and regulating Qi,which have value for the current cough diagnosis and treatment.
CoughReducing excess and regulating QiMedication ruleData mining
NETL
NSTL
万方数据
