A review on the correlation between functional dyspepsia and visceral hypersensitivity
Functional dyspepsia,a common disease of the digestive system,is characterised by recurrent and prolonged episodes.Its clinical manifestations include chronic or recurrent epigastric pain,bloating,nausea,vomiting and diarrhoea.Its pathogenesis is related to various factors such as visceral hypersensitivity,gastrointestinal motility disorders,Helicobacter pylori infection,increased gastric acid secretion,microbial dysbiosis and mental disorders.In recent years,the increasing incidence of the disease due to the accelerated pace of life and changes of diet structure has attracted widespread attention from clinical practitioners.Visceral hypersensitivity is an important pathological mechanism of functional dyspepsia.The pathogenesis is extremely complex,mainly caused by increased central sensitivity,receptor activation,transmitter release,etc..In terms of the treatment,Western medicine focuses on interventions on neurotransmitters and receptors,and also pays attenttion to the influence of psychological status of patients on the degree of disease progression.The use of a variety of medicines can effectively reduce a series of adverse reactions caused by visceral hypersensitivity,and improve the quality of life of patients.TCM has unique advantages in the treatment of functional dyspepsia,as it is able to provide a multi-dimensional,multi-faceted and multi-targeted holistic approach.Currently,research on the relationship between functional dyspepsia and visceral hypersensitivity,as well as TCM interventions,is still in the early stages of exploration.Exploring the relationship between functional dyspepsia and visceral hypersensitivity has implications for guiding clinical treatment of the disease as well as new medicine development.In this paper,from the perspective of visceral hypersensitivity,the relevant literature is comprehensively collected and collated,and the current research progress on the relationship between visceral hypersensitivity and functional dyspepsia is systematically reviewed,providing a theoretical basis for a more in-depth exploration of the relationship between the two in the future,and also providing new ideas for the targeted treatment of functional dyspepsia.
Functional dyspepsiaVisceral hypersensitivityTCM treatmentWestern medicine treatment
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万方数据
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