Professor SHI Zhexin's experience in treating primary myelofibrosis
Primary myelofibrosis characterized by different degrees of fibrous tissue proliferation in the bone marrow is one of myeloproliferative neoplasms.Primary myelofibrosis is a hematological disease,which is often accompanied by a series of disease-specific symptoms such as spleen enlargement,fatigue,and early satiety caused by different degrees of anemia,leukocytosis,and extramedullary hematopoiesis.A few can progress to acute leukemia,which seriously affects the quality of life of patients.Traditional Chinese medicine has its own advantages and characteristics in treating primary myelofibrosis.Professor SHI Zhexin has been engaged in the clinical work of integrated TCM and Western medicine on hematological diseases for many years,concludes that the TCM pathogenesis of the disease is closely related to the dysfunction of liver and spleen viscera.In the process of disease occurrence and development,phlegm turbidity and blood stasis pathology product generated and accumulated gradually,forming the splenomegaly,and toxic production was caused by excessive pathogenic factors,and the pathogenic toxin invaded the bone marrow.The lesion is located in the bone marrow,resulting in Qi(气)and blood iniury,and the hepatosplenomegaly is obvious.Focusing on its core pathogenesis,Professor SHI Zhexin adopted the combination of disease differentiation and syndrome differentiation to treat the disease.The professor believes that the key to the treatment of bone fiber is to promote blood circulation and remove blood stasis,and to eliminate phlegm and detoxification.At the same time,the teacher emphasized the importance of taking care of the spleen and stomach,nourishing the acquired to consolidate the congenital,distinguishing the pathogenesis of fatigue and disease,and administering the method of replenishing or dissolving Qi.The clinical effect of TCM on primary myelofibrosis is better,so Professor Shi Zhexin's experience in the treatment of primary myelofibrosis in combination with a medical case was summarized,in order to provide a certain reference for clinical practice.
Primary myelofibrosisMedication experiencePromote blood circulation and remove blood stasis
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