首页|自拟葛红汤联合注射用丹参多酚酸、美托洛尔治疗老年稳定型心绞痛的效果研究

自拟葛红汤联合注射用丹参多酚酸、美托洛尔治疗老年稳定型心绞痛的效果研究

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目的:探究自拟葛红汤联合注射用丹参多酚酸和美托洛尔对稳定型心绞痛老年患者的治疗效果.方法:从2020年9月-2022年4月接受治疗的稳定型心绞痛老年患者中选取94例作为研究对象,并按随机分组法分成对照组和研究组,每组47例.对照组采用注射用丹参多酚酸+口服美托洛尔,研究组在注射用丹参多酚酸+口服美托洛尔的基础上结合自拟葛红汤治疗,疗程均为1个月.比较两组的疗效、主要症状(发作次数、时间、疼痛程度、硝酸甘油的使用剂量)、心功能指标(左心室舒张末期内径、左心室收缩末期内径、左心室射血分数)和不良反应发生例数.结果:研究组治疗后的总有效率高于对照组(P<0.05);两组治疗后主要症状的发作次数、时间、疼痛程度和硝酸甘油的使用剂量均低于本组治疗前(P<0.05),且研究组的各项指标均低于对照组(P<0.05);两组治疗后左心室舒张末期内径、左心室收缩末期内径均低于本组治疗前,左心室射血分数高于本组治疗前(P<0.05),且研究组的各项指标均优于对照组(P<0.05);研究组的不良反应发生率低于对照组(P<0.05).结论:自拟葛红汤联合注射用丹参多酚酸和美托洛尔治疗稳定型心绞痛老年患者的效果较为显著,能缓解临床症状,改善心功能指标,减少不良反应.
A study on the effects of the Gehong decoction plus salvianolic acids injection and metoprolol on senile stable angina pectoris
Objective:To investigate the therapeutic effect of the Gehong decoction(自拟葛红汤)plus salvianolic acids injection and metoprolol on senile stable angina pectoris.Methods:A total of 94 cases of senile stable angina pectoris who received treatment from September 2020 to April 2022 were selected as research objects,and were randomly divided into the control group(47 cases)and the study group(47 cases).The control group received salvianolic acids injection and metoprolol,while the study group received the Gehong decoction more,with a course of treatment of 1 month.The therapeutic effect,main symptoms(number of attacks,duration,degree of pain,dosage of nitroglycerin),cardiac function indexes(LVEDD,LVESD,LVEF)and adverse reactions were compared between the two groups.Results:The total effective rate in the study group was higher than that in the control group(P<0.05).After treatment,number of attacks,duration,degree of pain,dosage of nitroglycerin in the two groups were lower than those before treatment(P<0.05),and the indexes in the study group were lower than those in the control group(P<0.05).After treatment,LVEDD and LVESD in both groups were lower than those before treatment,LVEF was higher than those before treatment(P<0.05),and the three indexes in the study group were better than those in the control group(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group(P<0.05).Conclusion:The Gehong decoction plus salvianolic acids injection and metoprolol has a significant effect on senile stable angina pectoris,which can alleviate clinical symptoms,improve cardiac function indexes and reduce adverse reactions.

The Gehong decoctionSalvianolic acids injectionMetoprololSenile stable angina pectoris

张开平、黄江、张继红

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湖北省远安县中医医院,湖北 远安,444200

三峡大学附属第二人民医院/宜昌市中西医结合医院,湖北 宜昌,443000

自拟葛红汤 注射用丹参多酚酸 美托洛尔 老年稳定型心绞痛

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(11)