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系统性红斑狼疮皮肤黏膜病变的中医研究进展

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系统性红斑狼疮是一种典型的自身免疫性疾病,皮肤黏膜的损害是系统性红斑狼疮的特征性症状,典型表现有蝶形红斑、雷诺现象、血管炎、光过敏、脱发、口腔溃疡等.目前,对于系统性红斑狼疮皮肤受累的一线治疗还是以西药为主,包括以激素为主的局部用药、抗疟药和全身用激素.现今医疗知识有效普及,患者虽未谈激素色变,但对于激素的使用还是有一定的顾虑.而中医药治疗历史悠久,对系统性红斑狼疮皮肤黏膜病变的治疗效果显著,不良反应小,治法多样,易于被接受,不仅缓解了患者的病痛,还树立了患者对治疗的信心.系统性红斑狼疮皮肤黏膜病变的病因病机可概括为虚、瘀、毒三者:虚指气血亏虚,瘀指血脉瘀滞,毒多指外感温热之邪.文章基于整体观念、辨证论治的中医基本特点,对系统性红斑狼疮皮肤黏膜病变的中医治疗进行综述,从传承已久的古方、现代医家的经验方及单味中药入手,探讨其疗效,列举中药熏洗、中药外敷、针灸、按摩等中医外治法,体现了中医的优势.
A review on treating cutaneous mucosal lesions of systemic lupus erythematosus in TCM
Systemic lupus erythematosus is a typical autoimmune disease,and the damage of the skin and mucosa is the characteristic symptom of systemic lupus erythematosus,and its typical manifestations include butterfly erythema,Rayaud's phenomenon,vasculitis,photoallergy,alopecia,oral ulcers and so on.At present,the first-line treatment for skin involvement of systemic lupus erythematosus is still dominated by Western drugs,including hormone-based local drugs,antimalarial drugs and systemic hormones.With the effective popularization of medical knowledge nowadays,although patients are not nervous when talking about hormones,they still have certain concerns about the use of hormones.TCM has a long history of treatment,the effect on skin and mucous membrane lesions is remarkable,the adverse reactions are small,the treatment methods are various,easy to accept,not only alleviate the pain of patients,but also establish the confidence of patients in treatment.The etiology and pathogenesis of skin and mucous membrane lesions of systemic lupus erythematosus can be summarized as asthenia,stasis and toxicity:asthenia refers to deficiency of Qi(气)and blood,stasis refers to blood stasis,and toxicity mainly refers to the evil of external warm heat.This article reviews the treatment of skin and mucous membrane lesions in systemic lupus erythematosus based on the basic characteristics of the holistic concept and syndrome differentiation of TCM.This paper discusses the curative effects of TCM empirical prescription of ancient masters and modern practitioners,single Chinese medicine,and TCM external therapies,including TCM fumigation,external application,acupuncture and massage,which reflect the advantages of TCM.

Systemic lupus erythematosusSkin mucosal lesionsEtiology and pathogenesisTCM treatment

林风至、于静、金明秀

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辽宁中医药大学,辽宁 沈阳,110847

辽宁中医药大学附属医院,辽宁 沈阳,110032

系统性红斑狼疮 皮肤黏膜病变 病因病机 中医治疗

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(11)