Application of wind-drugs in the treatment of diarrhea-predominant irritable bowel syndrome
Diarrhea-predominant irritable bowel syndrome(IBS-D)is the most common disease in clinical practice,characterized by chronic,recurrent abdominal pain or discomfort,often accompanied by changed bowel habits,and lack of clinical symptoms explained by organic diseases.Modern medicine believes that the pathophysiological mechanism of IBS-D is not clear,only knowing that its mechanism is related to visceral sensitivity,abnormal intestinal movement,intestinal infection and inflammation,psychoneurotic factors,immune factors,autonomic nervous dysfunction,intestinal microbial imbalance,intestinal permeability,etc..At present,most of the traditional Chinese medicine theories believe that the basis of the disease is spleen deficiency and dampness,but with liver depression as the symptom,spleen deficiency as the basis,liver depression and spleen deficiency are mutual influence,mutual causation,and the key to the pathogenesis;intestinal wind internal disturbance is the key to the pathogenesis of the disease.The long course causes spleen Yang(阳)deficiency,can involve kidney Yang,fire failure of Mingmen(命门)kidney Yang causes the spleen and stomach deficiency,so the water and valley are not changed and diarrhea is more serious.At present,the effect of western medicine is not good,and the use of traditional Chinese medicine can achieve a certain success,especially the use of wind-drugs is more important.Wind-drugs are thin and light,with the characteristics of ascending,evacuating and moving,and the functions of regulating Qi(气)movement of the spleen and stomach,lifting Yang in the spleen,strengthening the spleen and relieving the dampness,soothing the liver and gallbladder,etc..Pharmacological studies in modern Western medicine show that wind-medicine has the functions of anti-allergy,immune regulation,anti-inflammatory,gastrointestinal peristalsis,bacteriostasis and analgesia,so if the clinical effect is not good,wind-drugs can be added according to the symptoms of patients.Because of its remarkable curative effect,it is recommended by many physicians in clinical medicine for the treatment of IBS-D.
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