Research progress of ferroptosis in nervous system and intervention of traditional Chinese Medicine
The incidence of central nervous system diseases(CNS)is increasing year by year,but the pathogenesis of some diseases is not clear because of its complex etiology.Ferroptosis is a new form of programmed cell death.Studies have shown that ferroptosis is involved in the development of some neurological disorder through iron metabolism,amino acid metabolism and lipid peroxidation reactions,how to intervene in the occurrence and development of related diseases byregulating cell ferroptosis has become a hotspot and focus of etiological research and treatment.In recent years,a variety of traditional Chinese medicines have been shown to intervene in neurological disorder by modulating ferroptosis.This article summarizes the possible mechanism of ferroptosis,discusses the relationship between ferroptosis and CNS diseases,and summarizes the research progress of traditional Chinese medicine in the mechanism of ferroptosis,in order to provide more ideas for the study of ferroptosis in neurological disorder.
FerroptosisNervous system diseaseTraditional Chinese medicine
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