A review on the role of inflammatory damage in target organ damage in hypertension and the TCM treatment
Left ventricular hypertrophy,heart failure,chronic kidney disease,stroke,atherosclerosis and other complications caused by target organ damage caused by hypertension seriously endanger human health.Studies have shown that inflamromatory damage is one of the mechanisms of target organ damage of hypertension,and inflammatory reaction runs through the whole process of target organ daofmage of hypertension,such as heart,kidney,brain and artery damages and so on.In recent years,under the guidance of the holistic concept,syndrome differentiation and treatment,preventive treatment of disease and other traditional Chinese medicine theories,TCM has a good application prospect for the prevention and treatment of hypertension target organ damage.Traditional Chinese medicine has the advantages of multi-target,multi-system,individualization,small adverse reactions and high safety.It can play the role of controlling blood pressure,anti-inflammatory,and protecting vascular endothelial function and other effects to intervene the target organ damage of hypertension.It is an effective measure to prevent and treat the target organ damage of hypertension.Traditional Chinese medicine believes that the target organ damage of hypertension belongs to deficiency of origin and excess of symptoms,which should be treated by strengthening the body and eliminating pathogenic factors,and flexibly using the methods of nourishing Yin(阴),benefiting Qi(气),promoting blood circulation,resolving phlegm,expelling wind and clearing heat.Inflammatory injury is the key mediator to induce hypertension target organ damages.TCM intervention and regulation of the level of inflammatory factors and inflammatory response is of great significance in improving the process of hypertension target organ damage.Experiments of TCM compounds,TCM single prescription and TCM monomer have proved that many TCM medicines can inhibit the inflammatory response by regulating inflammatory factors and inflammatory signaling pathways,thus improving the damage of target organs of hypertension.Therefore,from the perspective of inflammatory injury,this paper discusses its correlation with the damage of target organs of hypertension and TCM treatment strategies.It provides theoretical basis for preventing and treating hypertension target organ damage by regulating inflammation injury in traditional Chinese medicine in clinic.
HypertensionTarget organ damageInflammatory damageTraditional Chinese medicine
万方数据
维普
