Clinical efficacy of Yiqi Touxie decoction on elderly multi-drug resistant bacterial pneumonia based on latent pathogenic factor theory
Objective:To evaluate the clinical effect of Yiqi Touxie decoction(益气透邪方)on elderly multi-drug resistant bacterial pneumonia in intensive care department based on conventional Western medicine treatment.Methods:A total of 80 elderly patients with multi-drug-resistant bacterial pneumonia admitted to the Department of Intensive Care Medicine,Affiliated Hospital of Gansu University of Chinese Medicine from February 2017 to October 2021 were randomly divided into the TCM treatment group and the control group.The control group was given routine treatment,and the TCM treatment group was supplemented with Yiqi Touxie decoction on the basis of routine treatment,and the course of treatment was 7 days.The TCM syndrome scores,C-reactive protein(CRP),procalcitonin(PCT),interleukin-6(IL-6),clinical pulmonary infection score(CPIS),oxygenation index(P/F),drug resistant bacteria clearance rate and 28 day mortality,in the two groups after treatment were recorded.Results:The total effective rate in the TCM treatment group and the control group were 92.50％(37/40)and 70.00％(28/40),respectively,and the curative effect in the TCM treatment group was better than that in the control group(P＜0.05).Compared with those before treatment,TCM syndrome score,CPIS score,CRP,PCT and IL-6 were all decreased in both groups after treatment,and the decrease was more obvious in the TCM treatment group(P＜0.05);compared with that before treatment,P/F was increased in both groups,and the improvement was more significant in the TCM treatment group(P＜0.05).The clearance rate of drug-resistant bacteria was 37.5％in the TCM treatment group and 27.5％in the control group(P＞0.05),and there was no significant difference between the two groups.There was no significant difference in 28 day mortality between the two groups(P＞0.05).Conclusion:On the basis of conventional western medicine treatment,the application of modified Yiqi Touxie decoction can significantly alleviate the clinical symptoms,reduce the inflammatory response,improve the oxygenation of patients in the treatment of elderly multi-drug resistant bacterial pneumonia.The clinical effect of Yiqi Touxie decoction is positive.
万方数据
维普
