A Meta-analysis of the efficacy and safety of internal heat acupuncture in the treatment of LDH
Objective:To systematically evaluate the efficacy and safety of internal heat acupuncture alone or combined therapy in the treatment of lumbar disc herniation.Methods:The studies in CNKI,CBM,VIP,Wanfang Database,Pubmed,Web of Science,Cochrance library and other domestic and foreign databases were searched by computer,and the search time was from the establishment of the databse to December 2022.Randomized controlled trials of internal heat acupuncture alone or combined therapy in the treatment of lumbar disc hemiation were searched.Data extraction and literature screening were carried out independently by two researchers,and methodological quality evaluation was carried out on the 29 studies finally included,and statistical analysis was performed using Revman 5.3 software.Results:Meta-analysis showed that compared with the single treatment of electroacupuncture,warm acupuncture,acupuncture,western medicine,lumbar traction or combined therapy(traditional Chinese medicine,lumbar traction,other treatments)in the control group,the overall clinical response rate in the internal heat acupuncture group was improved(RR=1.20,95％CI[1.16,1.24],P＜0.001),pain was reduced(MD=-1.58,95％CI[-1.78,-1.38],P＜0.000 01),and lumbar function was improved(MD=5.45,95％CI[4.86,6.03],P＜0.000 01),the internal heat acupuncture group were better than the control group in increased lumbar flexion range(MD=1.61,95％CI[1.35,1.87],P＜0.000 01),decreasing inflammatory factors(TNF-α,PEG2)and promoting β-endorphin secretion(P＜0.05).The difference was statistically significant.Adverse events during the treatment of internal heat injection were not reported or mentioned,and inverted funnel plot analysis indicated possible publication bias of the included studies.Conclusion:Internal heat acupuncture can significantly improve the clinical efficacy,promote lumbar spine function,relieve clinical symptoms,and it has high safety,which is worthy of clinical promotion.However,due to the quality and methodological limitations of the included literature,the conclusion of this review needs to be further confirmed by high-quality,multi-centre,and large-sample RCTs.
万方数据
维普
